| 9/1/2016 | Millsaps | 25 | at | Belhaven | 28 | SAA | ||
| 9/3/2016 | Southwestern Assemblies of God | 27 | at | Howard Payne | 21 | CSFL (NAIA) | ||
| Huntingdon AL | 52 | at | Louisiana College | 49 | USASC | |||
| Ohio Wesleyan | 0 | at | Mary Hardin-Baylor | 56 | NCA | |||
| Hardin-Simmons | 26 | at | Southwestern Texas | 3 | @ SCAC | |||
| East Texas Baptist | 44 | at | Texas Lutheran | 20 | @ SCAC | |||
| Sul Ross State | 6 | at | Texas-Permian Basin | 27 | @ LSC (D2) | |||
| 9/10/2016 | Howard Payne | 17 | at | Austin | 19 | @ SCAC | ||
| Southwestern Assemblies of God | 23 | at | East Texas Baptist | 85 | CSFL (NAIA) | |||
| McMurry | 17 | at | Southwestern Texas | 24 | @ SCAC | |||
| Louisiana College | 49 | at | Texas College | 18 | @ CSFL (NAIA) | |||
| Mary Hardin-Baylor | 56 | at | Texas Lutheran | 21 | @ SCAC | |||
| Belhaven | 13 | at | Wisconsin-Whitewater | 59 | @ WIAC | |||
| Sul Ross State | 48 | at | Wayland Baptist | 27 | @ CSFL (NAIA) | |||
| 9/17/2016 | Southwestern Texas | 23 | at | East Texas Baptist | 33 | SCAC | ||
| Belhaven | 21 | at | Huntingdon AL | 65 | @ USASC | |||
| Texas Lutheran | 28 | at | Louisiana College | 58 | SCAC | |||
| Linfield | 27 | at | Mary Hardin-Baylor | 66 | NWC | |||
| Texas College | 6 | at | McMurry | 63 | CSFL (NAIA) | |||
| Arizona Christian | 30 | at | Sul Ross State | 27 | OT | CSFL (NAIA) | ||
| Hardin-Simmons | 61 | at | Southwestern Assemblies of God | 24 | @ CSFL (NAIA) | |||
| Howard Payne | 37 | at | Wayland Baptist | 40 | @ CSFL (NAIA) | |||
| 9/24/2016 | Texas Lutheran | 38 | at | Hardin-Simmons | 48 | SCAC | ||
| 10/1/2016 | East Texas Baptist | 60 | at | Belhaven | 47 | |||
| Sul Ross State | 29 | at | Hardin-Simmons | 53 | ||||
| Howard Payne | 7 | at | Louisiana College | 35 | ||||
| McMurry | 3 | at | Mary Hardin-Baylor | 66 | ||||
| 10/8/2016 | Mary Hardin-Baylor | 59 | at | Howard Payne | 10 | |||
| Hardin-Simmons | 42 | at | Louisiana College | 21 | ||||
| East Texas Baptist | 67 | at | McMurry | 31 | ||||
| Belhaven | 36 | at | Sul Ross State | 52 | ||||
| 10/15/2016 | McMurry | 56 | at | Belhaven | 7 | |||
| Mary Hardin-Baylor | 59 | at | East Texas Baptist | 22 | ||||
| Howard Payne | 15 | at | Hardin-Simmons | 54 | ||||
| Louisiana College | 14 | at | Sul Ross State | 21 | ||||
| 10/22/2016 | Howard Payne | 14 | at | East Texas Baptist | 76 | |||
| Belhaven | 30 | at | Louisiana College | 52 | ||||
| Hardin-Simmons | 15 | at | Mary Hardin-Baylor | 20 | ||||
| Sul Ross State | 35 | at | McMurry | 21 | ||||
| 10/29/2016 | Hardin-Simmons | 55 | at | Belhaven | 21 | |||
| McMurry | 41 | at | Howard Payne | 6 | ||||
| East Texas Baptist | 64 | at | Louisiana College | 62 | ||||
| Mary Hardin-Baylor | 59 | at | Sul Ross State | 10 | ||||
| 11/5/2016 | Mary Hardin-Baylor | 59 | at | Belhaven | 21 | |||
| East Texas Baptist | 30 | at | Hardin-Simmons | 66 | ||||
| Louisiana College | 28 | at | McMurry | 34 | ||||
| Howard Payne | 8 | at | Sul Ross State | 42 | ||||
| 11/12/2016 | Sul Ross State | 47 | at | East Texas Baptist | 18 | |||
| McMurry | 17 | at | Hardin-Simmons | 47 | ||||
| Belhaven | 50 | at | Howard Payne | 45 | ||||
| Louisiana College | 7 | at | Mary Hardin-Baylor | 63 | ||||
| 11/19/2016 | Linfield | 24 | at | Hardin-Simmons | 10 | NWC | ||
| Redlands | 28 | at | Mary Hardin-Baylor | 50 | SCIAC | |||
| 11/26/2016 | Linfield | 10 | at | Mary Hardin-Baylor | 27 | NWC | ||
| 12/3/2016 | Wheaton | 16 | at | Mary Hardin-Baylor | 38 | D3 Quarterfinal | CCIW | |
| 12/10/2016 | Mount Union | 12 | at | Mary Hardin-Baylor | 14 | D3 Semifinal | OAC | |
| 12/16/2016 | Mary Hardin-Baylor | 10 | vs | Wisconsin-Oshkosh | 7 | D3 Championship (Salem VA) | vs WIAC |