| 9/5/2015 | Berry (7-3) | 17 | at | Maryville | 43 | SAA | ||
| 9/10/2015 | Maryville | 28 | at | East Tennessee St (2-9) | 21 | at IndFCS | ||
| 9/19/2015 | Maryville | 30 | at | Emory & Henry (6-4) | 13 | at ODC | ||
| 10/3/2015 | Methodist (4-6,2-5) | 23 | at | Maryville | 29 | |||
| 10/10/2015 | Maryville | 7 | at | North Carolina Wesleyan (5-5,5-2) | 24 | |||
| 10/17/2015 | Ferrum (2-8,2-5) | 37 | at | Maryville | 70 | |||
| 10/24/2015 | Maryville | 31 | at | Averett (2-7,2-4) | 26 | |||
| 10/31/2015 | LaGrange (2-7,2-4) | 31 | at | Maryville | 38 | |||
| 11/7/2015 | Maryville | 14 | at | Huntingdon AL (10-2,7-0) | 38 | |||
| 11/14/2015 | Greensboro (3-7,2-5) | 3 | at | Maryville | 52 |
| vs Maryville | vs Other Opponents | Maryville compared to OOs | |
| Record: | 2-8 | 41-50 | |
| Points Scored: | 23.30 | 28.10 | 4.80 |
| Points Allowed: | 34.20 | 32.11 | 2.09 |
| Margin: | -10.90 | -4.01 | 6.89 |
| Total Points: | 57.50 | 60.21 | -2.71 |