| 9/5/2015 | Wagner (1-10) | 16 | at | Rice | 56 | NE (1AA) | ||
| 9/12/2015 | Rice | 28 | at | Texas (5-7) | 42 | at B12 | ||
| 9/19/2015 | Rice | 28 | at | North Texas (1-11,1-7) | 24 | |||
| 9/26/2015 | Rice | 17 | at | Baylor (10-3) | 70 | at B12 | ||
| 10/3/2015 | Western Kentucky (12-2,9-0) | 49 | at | Rice | 10 | |||
| 10/10/2015 | Rice | 27 | at | Florida Atlantic (3-9,3-5) | 26 | |||
| 10/24/2015 | Army (2-10) | 31 | at | Rice | 38 | Ind | ||
| 10/30/2015 | Louisiana Tech (9-4,6-2) | 42 | at | Rice | 17 | |||
| 11/6/2015 | Rice | 21 | at | UTEP (5-7,3-5) | 24 | |||
| 11/14/2015 | Southern Miss (9-5,7-2) | 65 | at | Rice | 10 | |||
| 11/21/2015 | Rice | 24 | at | Texas-San Antonio (3-9,3-5) | 34 | |||
| 11/28/2015 | UNC-Charlotte (2-10,0-8) | 7 | at | Rice | 27 |
| vs Rice | vs Other Opponents | Rice compared to OOs | |
| Record: | 7-5 | 55-82 | |
| Points Scored: | 35.83 | 27.61 | -8.22 |
| Points Allowed: | 25.25 | 31.35 | -6.10 |
| Margin: | 10.58 | -3.74 | -14.32 |
| Total Points: | 61.08 | 58.96 | 2.12 |