| 9/3/2015 | Azusa Pacific | 27 | at | West Texas A&M | 24 | | | @ LSC |
| 9/5/2015 | South Dakota Tech | 28 | at | Colorado Mines | 63 | | | @ RMAC |
| Central Washington | 14 | at | Colorado State-Pueblo | 41 | | | @ RMAC |
| Colorado Mesa | 43 | at | Dixie State | 3 | | | RMAC |
| Western Oregon | 20 | at | Humboldt State | 29 | | | |
| 9/10/2015 | Central Washington | 20 | at | Dixie State | 49 | | | |
| 9/12/2015 | Humboldt State | 62 | at | Azusa Pacific | 41 | | | |
| Black Hills State | 26 | at | South Dakota Tech | 28 | | | RMAC |
| Simon Fraser | 14 | at | Western Oregon | 31 | | | |
| 9/19/2015 | Western Oregon | 19 | at | Central Washington | 40 | | | |
| Dixie State | 7 | at | Humboldt State | 66 | | | |
| Azusa Pacific | 16 | at | Simon Fraser | 10 | | | |
| South Dakota Tech | 49 | at | Wisconsin-River Falls | 22 | | | @ WIAC (D3) |
| 9/26/2015 | Simon Fraser | 7 | vs | Central Washington | 40 | | Bothell WA | |
| Azusa Pacific | 34 | at | Dixie State | 5 | | | |
| Western Oregon | 0 | at | Portland State | 31 | | | @ BSky (1AA) |
| Lyon | 10 | at | South Dakota Tech | 51 | | | CSFL (NAIA) |
| 10/2/2015 | Western Oregon | 42 | at | Dixie State | 24 | | | |
| 10/3/2015 | Central Washington | 24 | at | Azusa Pacific | 21 | | | |
| Humboldt State | 59 | at | South Dakota Tech | 10 | | | |
| 10/10/2015 | South Dakota Tech | 49 | at | Central Washington | 44 | | | |
| Azusa Pacific | 16 | at | Humboldt State | 34 | | | |
| Dixie State | 38 | at | Simon Fraser | 35 | | | |
| North Alabama | 22 | at | Western Oregon | 24 | | | GSC |
| 10/17/2015 | Dixie State | 14 | at | Azusa Pacific | 61 | | | |
| Humboldt State | 10 | at | Midwestern State | 35 | | | @ LSC |
| Simon Fraser | 0 | at | South Dakota Tech | 19 | | | |
| Central Washington | 25 | at | Western Oregon | 31 | | | |
| 10/24/2015 | South Dakota Tech | 27 | at | Azusa Pacific | 56 | | | |
| Humboldt State | 42 | at | Central Washington | 17 | | | |
| Western Oregon | 37 | at | Simon Fraser | 26 | | | |
| 10/31/2015 | Simon Fraser | 0 | at | Humboldt State | 57 | | | |
| Dixie State | 48 | at | South Dakota Tech | 25 | | | |
| Azusa Pacific | 14 | at | Western Oregon | 17 | | | |
| 11/7/2015 | Humboldt State | 57 | at | Dixie State | 14 | | | |
| South Dakota Tech | 15 | at | Western Oregon | 33 | | | |
| 11/14/2015 | Simon Fraser | 17 | at | Azusa Pacific | 38 | | | |
| Dixie State | 28 | at | Central Washington | 34 | | | |
| William Jewell | 14 | at | South Dakota Tech | 35 | | | GLV |
| Humboldt State | 29 | at | Western Oregon | 13 | | | |
| 11/21/2015 | Augustana SD | 31 | at | Humboldt State | 45 | | NCAA D2 Championship - First Round | NSIC |
| 11/28/2015 | Humboldt State | 7 | at | Northwest Missouri State | 54 | | NCAA D2 Championship - Second Round | @ MAIAA |