| 8/29/2015 | Tabor (11-2) | 45 | at | Lyon | 21 | KCAC | ||
| 9/5/2015 | Lindsey Wilson (8-3) | 76 | at | Lyon | 10 | MSC | ||
| 9/12/2015 | Lyon | 7 | at | Hendrix (8-3) | 42 | at SAA | ||
| 9/26/2015 | Lyon | 10 | at | South Dakota Tech (6-5) | 51 | at GNWAC | ||
| 10/3/2015 | Bacone (2-9,2-4) | 37 | at | Lyon | 35 | |||
| 10/10/2015 | Lyon | 7 | at | Southwestern Assemblies of God (8-3,4-2) | 47 | |||
| 10/17/2015 | Lyon | 18 | at | Arizona Christian (6-3,6-0) | 70 | |||
| 10/24/2015 | Austin (5-5) | 28 | at | Lyon | 21 | OT | SCAC (D3) | |
| 10/31/2015 | Langston (7-3,5-1) | 48 | at | Lyon | 14 | |||
| 11/7/2015 | Lyon | 14 | at | Texas College (2-8,2-4) | 21 | |||
| 11/14/2015 | Wayland Baptist (4-6,2-4) | 51 | at | Lyon | 30 |
| vs Lyon | vs Other Opponents | Lyon compared to OOs | |
| Record: | 11-0 | 56-50 | |
| Points Scored: | 46.91 | 27.42 | -19.49 |
| Points Allowed: | 17.00 | 30.92 | -13.92 |
| Margin: | 29.91 | -3.50 | -33.41 |
| Total Points: | 63.91 | 58.34 | 5.57 |