| 9/1/2012 | Marshall | 34 | at | West Virginia (7-6) | 69 | at B12 | ||
| 9/8/2012 | Western Carolina (1-10) | 24 | at | Marshall | 52 | SoCon (1AA) | ||
| 9/15/2012 | Ohio (9-4) | 27 | at | Marshall | 24 | MAC | ||
| 9/22/2012 | Marshall | 54 | at | Rice (7-6,4-4) | 51 | 2OT | ||
| 9/29/2012 | Marshall | 41 | at | Purdue (6-7) | 51 | at B10 | ||
| 10/6/2012 | Tulsa (11-3,8-1) | 45 | at | Marshall | 38 | |||
| 10/20/2012 | Marshall | 59 | at | Southern Miss (0-12,0-8) | 24 | |||
| 10/27/2012 | UCF (10-4,7-2) | 54 | at | Marshall | 17 | |||
| 11/3/2012 | Memphis (4-8,4-4) | 28 | at | Marshall | 38 | |||
| 11/10/2012 | Marshall | 31 | at | UAB (3-9,2-6) | 38 | |||
| 11/17/2012 | Houston (5-7,4-4) | 41 | at | Marshall | 44 | |||
| 11/23/2012 | Marshall | 59 | at | East Carolina (8-5,7-1) | 65 | 2OT |
| vs Marshall | vs Other Opponents | Marshall compared to OOs | |
| Record: | 7-5 | 64-76 | |
| Points Scored: | 43.08 | 29.29 | -13.79 |
| Points Allowed: | 40.92 | 30.86 | 10.06 |
| Margin: | 2.16 | -1.57 | -3.73 |
| Total Points: | 84.00 | 60.15 | 23.85 |