| 9/1/2012 | North Texas (4-8) | 14 | at | LSU | 41 | SBC | ||
| 9/8/2012 | Washington (7-6) | 3 | at | LSU | 41 | P12 | ||
| 9/15/2012 | Idaho (1-11) | 14 | at | LSU | 63 | WAC | ||
| 9/22/2012 | LSU | 12 | at | Auburn (3-9,0-8) | 10 | |||
| 9/29/2012 | Towson (7-4) | 22 | at | LSU | 38 | CAAF (1AA) | ||
| 10/6/2012 | LSU | 6 | at | Florida (11-2,7-1) | 14 | |||
| 10/13/2012 | South Carolina (11-2,6-2) | 21 | at | LSU | 23 | |||
| 10/20/2012 | LSU | 24 | at | Texas A&M (11-2,6-2) | 19 | |||
| 11/3/2012 | Alabama (13-1,8-1) | 21 | at | LSU | 17 | |||
| 11/10/2012 | Mississippi State (8-5,4-4) | 17 | at | LSU | 37 | |||
| 11/17/2012 | Mississippi (7-6,3-5) | 35 | at | LSU | 41 | |||
| 11/23/2012 | LSU | 20 | at | Arkansas (4-8,2-6) | 13 | |||
| 12/31/2012 | LSU | 24 | vs | Clemson (11-2) | 25 | Chick-fil-A Bowl | vs ACC |
| vs LSU | vs Other Opponents | LSU compared to OOs | |
| Record: | 3-10 | 95-56 | |
| Points Scored: | 17.54 | 30.34 | 12.80 |
| Points Allowed: | 29.77 | 23.87 | 5.90 |
| Margin: | -12.23 | 6.47 | 18.70 |
| Total Points: | 47.31 | 54.21 | -6.90 |