| 9/1/2012 | Muhlenberg | 27 | at | Apprentice | 7 | vs Cen | ||
| Texas Lutheran | 38 | at | Austin | 16 | vs ASWC | |||
| Wesley | 34 | at | East Texas Baptist | 14 | @ ASWC | |||
| Maryville | 33 | at | Huntingdon AL | 49 | vs USASC | |||
| Crown | 6 | at | Macalester | 53 | vs UMWAC | |||
| Haskell | 13 | at | Presentation | 26 | vs NAIAInd (NAIA) | |||
| Howard Payne | 7 | at | Trinity TX | 56 | vs ASWC | |||
| 9/8/2012 | East Texas Baptist | 17 | at | Austin | 7 | vs ASWC | ||
| Birmingham-Southern | 45 | at | Huntingdon AL | 38 | vs SCAC | |||
| Concordia WI | 13 | at | Macalester | 17 | vs NAC | |||
| Wesley | 17 | at | Salisbury | 7 | @ E8 | |||
| Trinity TX | 31 | at | Texas Lutheran | 7 | @ ASWC | |||
| Presentation | 29 | at | Waldorf | 47 | @ MSFA (NAIA) | |||
| 9/15/2012 | Apprentice | 13 | at | Greensboro | 20 | @ USASC | ||
| Huntingdon AL | 62 | at | LaGrange | 17 | @ USASC | |||
| Maranatha Baptist | 6 | at | Macalester | 49 | vs NAC | |||
| Northwestern MN | 35 | at | Presentation | 10 | vs UMWAC | |||
| Trinity TX | 35 | at | Sul Ross State | 62 | @ ASWC | |||
| Austin | 25 | at | Southwestern Assemblies of God | 17 | @ CSFL (NAIA) | |||
| Mary Hardin-Baylor | 32 | at | Wesley | 25 | vs ASWC | |||
| 9/22/2012 | Sewanee | 31 | at | Austin | 10 | vs SCAC | ||
| Apprentice | 7 | at | Gallaudet | 35 | @ ECFC | |||
| Huntingdon AL | 24 | at | Hampden-Sydney | 21 | @ ODC | |||
| Macalester | 17 | at | Lewis & Clark | 41 | @ NWC | |||
| Wesley | 25 | at | Louisiana College | 22 | @ ASWC | |||
| Presentation | 7 | at | Mayville State | 54 | @ NAIAInd (NAIA) | |||
| Mary Hardin-Baylor | 49 | at | Trinity TX | 28 | vs ASWC | |||
| 9/29/2012 | Bridgewater VA | 44 | at | Apprentice | 14 | vs ODC | ||
| Austin | 21 | at | Birmingham-Southern | 49 | @ SCAC | |||
| Ave Maria | 21 | at | Huntingdon AL | 42 | vs NAIAInd (NAIA) | |||
| Martin Luther | 17 | at | Presentation | 13 | vs UMWAC | |||
| Rhodes | 22 | at | Trinity TX | 30 | vs SCAC | |||
| 10/5/2012 | Southern Virginia | 20 | vs | Apprentice | 14 | Salem VA | vs NAIAInd (NAIA) | |
| 10/6/2012 | Rhodes | 27 | at | Austin | 13 | vs SCAC | ||
| Macalester | 20 | at | Carleton | 21 | @ MIA | |||
| Presentation | 20 | at | Crown | 41 | @ UMWAC | |||
| Huntingdon AL | 45 | at | Millsaps | 24 | @ SCAC | |||
| Birmingham-Southern | 17 | at | Wesley | 26 | vs SCAC | |||
| 10/13/2012 | Wayland Baptist | 23 | at | Austin | 24 | vs CSFL (NAIA) | ||
| Trinity TX | 30 | at | Birmingham-Southern | 21 | @ SCAC | |||
| Rhodes | 14 | at | Macalester | 0 | vs SCAC | |||
| Presentation | 6 | at | South Dakota Tech | 75 | @ D2Ind (D2) | |||
| Virginia U-Lynchburg | 7 | at | Wesley | 24 | vs None (Unk?) | |||
| 10/20/2012 | Trinity TX | 14 | at | Centre | 31 | @ SCAC | ||
| Trinity Bible | 0 | at | Macalester | 59 | vs None (Unk?) | |||
| Wesley | 30 | at | Menlo | 13 | @ NAIAInd (NAIA) | |||
| Presentation | 28 | at | Minnesota-Morris | 35 | @ UMWAC | |||
| 10/27/2012 | Centre | 17 | at | Austin | 0 | vs SCAC | ||
| Wesley | 31 | at | Huntingdon AL | 21 | ||||
| Macalester | 41 | at | Mayville State | 14 | @ NAIAInd (NAIA) | |||
| Apprentice | 14 | at | Point | 48 | @ NAIAInd (NAIA) | |||
| St Scholastica | 20 | at | Presentation | 17 | OT | vs UMWAC | ||
| Millsaps | 24 | at | Trinity TX | 35 | vs SCAC | |||
| 11/3/2012 | Augsburg | 58 | at | Macalester | 41 | vs MIA | ||
| Austin | 34 | at | Millsaps | 36 | @ SCAC | |||
| Huntingdon AL | 33 | at | Point | 19 | @ NAIAInd (NAIA) | |||
| Trinity Bible | 18 | at | Presentation | 50 | vs None (Unk?) | |||
| Trinity TX | 48 | at | Sewanee | 7 | @ SCAC | |||
| Apprentice | 0 | at | Wesley | 47 | ||||
| 11/10/2012 | Webber International | 13 | at | Apprentice | 12 | vs NAIAInd (NAIA) | ||
| Macalester | 45 | at | Hamline | 21 | @ MIA | |||
| Adrian | 17 | at | Huntingdon AL | 16 | vs MIAA | |||
| Austin | 13 | at | Trinity TX | 42 | ||||
| 11/17/2012 | Mount Ida | 14 | at | Wesley | 73 | Div 3 Playoffs 1st Round | vs ECFC | |
| 11/24/2012 | Cortland | 6 | at | Wesley | 56 | D3 Playoffs Round 2 | vs NJAC | |
| 12/1/2012 | Wesley | 20 | at | Mary Hardin-Baylor | 32 | D3 Quarterfinals | @ ASWC |