| 8/28/2010 | Baker Wildcats 14 @ Ottawa 24 | |
| 9/11/2010 | Ottawa 62 @ Bethel KS Threshers 23 | † |
| 9/18/2010 | Ottawa 24 @ McPherson Bulldogs 56 | † |
| 9/25/2010 | Sterling Warriors 34 @ Ottawa 39 | † |
| 10/2/2010 | Ottawa 51 @ Southwestern Moundbuilders 0 | † |
| 10/9/2010 | Tabor Bluejays 6 @ Ottawa 55 | † |
| 10/23/2010 | St Mary KS Spires 16 @ Ottawa 34 | † |
| 10/30/2010 | Ottawa 49 @ Kansas Wesleyan Coyotes 45 | † |
| 11/6/2010 | Ottawa 39 @ Bethany KS Terrible Swedes 33 | † |
| 11/13/2010 | Friends Falcons 21 @ Ottawa 54 | † |
| 11/20/2010 | Marian IN Knights 35 @ Ottawa 20 |