| 9/18/2010 | Stony Brook Seawolves 30 @ Brown 33 | |
| 9/25/2010 | Harvard Crimson 14 @ Brown 29 | † |
| 10/2/2010 | Brown 24 @ Rhode Island Rams 27 | |
| 10/9/2010 | Brown 13 @ Holy Cross Crusaders 17 | |
| 10/16/2010 | Brown 17 @ Princeton Tigers 13 | † |
| 10/23/2010 | Cornell Rams 14 @ Brown 27 | † |
| 10/30/2010 | Brown 7 @ Pennsylvania Quakers 24 | † |
| 11/6/2010 | Yale Bulldogs 27 @ Brown 24 | † |
| 11/13/2010 | Brown 35 @ Dartmouth Corsairs 28 | † |
| 11/20/2010 | Columbia Lions 16 @ Brown 38 | † |