| 9/4/2010 | San Jose State | 3 | @ | Alabama | 48 | ||||
| 9/11/2010 | Penn State | 3 | @ | Alabama | 24 | ||||
| 9/18/2010 | Alabama | 62 | @ | Duke | 13 | ||||
| 9/25/2010 | Alabama | 24 | @ | Arkansas | 20 | SEC | |||
| 10/2/2010 | Florida | 6 | @ | Alabama | 31 | SEC | |||
| 10/9/2010 | Alabama | 21 | @ | South Carolina | 35 | SEC | |||
| 10/16/2010 | Mississippi | 10 | @ | Alabama | 23 | SEC | |||
| 10/23/2010 | Alabama | 41 | @ | Tennessee | 10 | SEC | |||
| 11/6/2010 | Alabama | 21 | @ | LSU | 24 | SEC | |||
| 11/13/2010 | Mississippi State | 10 | @ | Alabama | 30 | SEC | |||
| 11/18/2010 | Georgia State NAIA | 7 | @ | Alabama | 63 | ||||
| 11/26/2010 | Auburn | 28 | @ | Alabama | 27 | SEC | |||
| 1/1/2011 | Alabama | 49 | vs | Michigan State | 7 | Orlando - Capital One Bowl |