| 8/30/2008 | North Texas | 6 | @ | Kansas St | 45 | ||||
| 9/6/2008 | Montana St | 10 | @ | Kansas St | 69 | ||||
| 9/17/2008 | Kansas St | 29 | @ | Louisville | 38 | ||||
| 9/27/2008 | UL Lafayette | 37 | @ | Kansas St | 45 | ||||
| 10/4/2008 | Texas Tech | 58 | @ | Kansas St | 28 | B12 | |||
| 10/11/2008 | Kansas St | 44 | @ | Texas A&M | 30 | B12 | |||
| 10/18/2008 | Kansas St | 13 | @ | Colorado | 14 | B12 | |||
| 10/25/2008 | Oklahoma | 58 | @ | Kansas St | 35 | B12 | |||
| 11/1/2008 | Kansas St | 21 | @ | Kansas | 52 | B12 | |||
| 11/8/2008 | Kansas St | 24 | @ | Missouri | 41 | B12 | |||
| 11/15/2008 | Nebraska | 56 | @ | Kansas St | 28 | B12 | |||
| 11/22/2008 | Iowa State | 30 | @ | Kansas St | 38 | B12 |