| 8/30/2007 | Tennessee Tech | 24 | @ | Eastern Illinois | 45 | OVC | |||
| 9/8/2007 | Eastern Illinois | 6 | @ | Purdue | 52 | ||||
| 9/15/2007 | Illinois St | 24 | @ | Eastern Illinois | 21 | ||||
| 9/22/2007 | Eastern Illinois | 54 | @ | Indiana St | 20 | ||||
| 9/29/2007 | Eastern Illinois | 31 | @ | SE Missouri St | 16 | OVC | |||
| 10/6/2007 | Eastern Kentucky | 28 | @ | Eastern Illinois | 21 | OVC | |||
| 10/13/2007 | Eastern Illinois | 27 | @ | Murray St | 24 | OVC | |||
| 10/20/2007 | Tennessee-Martin | 23 | @ | Eastern Illinois | 29 | OVC | |||
| 10/27/2007 | Eastern Illinois | 38 | @ | Tennessee St | 35 | OVC | |||
| 11/10/2007 | Eastern Illinois | 37 | @ | Jacksonville St | 23 | OVC | |||
| 11/17/2007 | Samford | 17 | @ | Eastern Illinois | 33 | OVC | |||
| 11/24/2007 | Eastern Illinois | 11 | @ | Southern Illinois | 30 |