| 9/1/2007 | Eastern Kentucky | 10 | @ | Kentucky | 50 | ||||
| 9/8/2007 | Western Carolina | 21 | @ | Eastern Kentucky | 45 | ||||
| 9/15/2007 | Eastern Kentucky | 6 | @ | Western Kentucky | 26 | ||||
| 9/22/2007 | Eastern Kentucky | 31 | @ | Jacksonville St | 20 | OVC | |||
| 9/29/2007 | Samford | 20 | @ | Eastern Kentucky | 43 | OVC | |||
| 10/6/2007 | Eastern Kentucky | 28 | @ | Eastern Illinois | 21 | OVC | |||
| 10/13/2007 | SE Missouri St | 17 | @ | Eastern Kentucky | 44 | OVC | |||
| 10/20/2007 | Tennessee St | 7 | @ | Eastern Kentucky | 49 | OVC | |||
| 10/27/2007 | Eastern Kentucky | 46 | @ | Murray St | 35 | OVC | |||
| 11/10/2007 | Eastern Kentucky | 28 | @ | Austin Peay | 14 | ||||
| 11/17/2007 | Tennessee Tech | 24 | @ | Eastern Kentucky | 38 | OVC | |||
| 11/24/2007 | Eastern Kentucky | 14 | @ | Richmond | 31 |