| 9/3/2005 | Miami-Ohio | 14 | @ | #4 Ohio State | 34 | ||||
| 9/10/2005 | Central Michigan | 38 | @ | Miami-Ohio | 37 | MAC | |||
| 9/17/2005 | Miami-Ohio | 27 | @ | Kent St | 10 | MAC | |||
| 9/28/2005 | Cincinnati | 16 | @ | Miami-Ohio | 44 | ||||
| 10/5/2005 | Miami-Ohio | 27 | @ | Northern Illinois | 38 | MAC | |||
| 10/15/2005 | Akron | 23 | @ | Miami-Ohio | 51 | MAC | |||
| 10/22/2005 | Miami-Ohio | 24 | @ | Eastern Michigan | 23 | MAC | |||
| 10/29/2005 | Miami-Ohio | 41 | @ | Temple | 14 | ||||
| 11/5/2005 | Buffalo | 13 | @ | Miami-Ohio | 54 | MAC | |||
| 11/15/2005 | Bowling Green | 42 | @ | Miami-Ohio | 14 | MAC | |||
| 11/21/2005 | Miami-Ohio | 38 | @ | Ohio | 7 | MAC |