| 9/4/2021 | Gustavus Adolphus (8-2) | 80 | at | Buena Vista | 58 | MIA | ||
| 9/11/2021 | Buena Vista | 58 | at | Northwestern MN (3-7) | 21 | at UMWAC | ||
| 9/18/2021 | Buena Vista | 34 | at | Loras (4-6,4-4) | 55 | |||
| 9/25/2021 | Luther (0-10,0-8) | 14 | at | Buena Vista | 32 | |||
| 10/2/2021 | Buena Vista | 16 | at | Dubuque (6-4,5-3) | 31 | |||
| 10/16/2021 | Nebraska Wesleyan (4-6,2-6) | 7 | at | Buena Vista | 50 | |||
| 10/23/2021 | Buena Vista | 50 | at | Simpson (1-9,1-7) | 19 | |||
| 10/30/2021 | Wartburg (7-3,6-2) | 20 | at | Buena Vista | 24 | |||
| 11/6/2021 | Buena Vista | 28 | at | Coe (8-2,6-2) | 31 | |||
| 11/13/2021 | Central IA (12-1,8-0) | 65 | at | Buena Vista | 6 |
| vs Buena Vista | vs Other Opponents | Buena Vista compared to OOs | |
| Record: | 5-5 | 48-45 | |
| Points Scored: | 34.30 | 29.71 | -4.59 |
| Points Allowed: | 35.60 | 29.97 | 5.63 |
| Margin: | -1.30 | -0.26 | 1.04 |
| Total Points: | 69.90 | 59.68 | 10.22 |