| 9/4/2021 | Simon Fraser | 0 | at | Idaho (4-7) | 68 | at BSky | ||
| 9/11/2021 | Simon Fraser | 20 | at | Linfield (11-1) | 56 | at NWC | ||
| 9/18/2021 | Central Washington (8-3,4-0) | 36 | at | Simon Fraser | 14 | |||
| 9/25/2021 | Western Oregon (4-6,2-2) | 24 | at | Simon Fraser | 7 | |||
| 10/2/2021 | Texas-Permian Basin (5-6) | at | Simon Fraser | Canceled | LSC | |||
| 10/16/2021 | Simon Fraser | 30 | at | Montana State-Northern (1-10) | 3 | at Front | ||
| 10/23/2021 | Simon Fraser | 10 | at | Angelo State (11-3) | 51 | at LSC | ||
| 10/30/2021 | Simon Fraser | 3 | at | Western Oregon (4-6,2-2) | 42 | |||
| 11/13/2021 | Simon Fraser | 0 | at | Central Washington (8-3,4-0) | 70 |
| vs Simon Fraser | vs Other Opponents | Simon Fraser compared to OOs | |
| Record: | 7-1 | 45-44 | |
| Points Scored: | 43.75 | 32.25 | -11.50 |
| Points Allowed: | 10.50 | 27.45 | -16.95 |
| Margin: | 33.25 | 4.80 | -28.45 |
| Total Points: | 54.25 | 59.70 | -5.45 |