| 9/2/2021 | The Citadel | 14 | at | Coastal Carolina (11-2) | 52 | at SBC | ||
| 9/11/2021 | Charleston Southern (4-6) | 38 | at | The Citadel | 21 | BigS | ||
| 9/18/2021 | North Greenville (5-6) | 13 | at | The Citadel | 45 | GSC (D2) | ||
| 10/2/2021 | VMI (6-5,4-4) | 24 | at | The Citadel | 35 | |||
| 10/9/2021 | The Citadel | 21 | at | East Tennessee St (11-2,7-1) | 48 | |||
| 10/16/2021 | The Citadel | 14 | at | Furman (6-5,4-4) | 24 | |||
| 10/23/2021 | Western Carolina (4-7,4-4) | 45 | at | The Citadel | 31 | |||
| 10/30/2021 | Mercer (7-3,6-2) | 34 | at | The Citadel | 7 | |||
| 11/6/2021 | The Citadel | 14 | at | Samford (4-7,3-5) | 35 | |||
| 11/13/2021 | Wofford (1-10,0-8) | 44 | at | The Citadel | 45 | OT | ||
| 11/20/2021 | The Citadel | 24 | at | Chattanooga (6-5,5-3) | 21 |
| vs The Citadel | vs Other Opponents | The Citadel compared to OOs | |
| Record: | 7-4 | 58-54 | |
| Points Scored: | 34.36 | 29.74 | -4.62 |
| Points Allowed: | 24.64 | 28.63 | -3.99 |
| Margin: | 9.72 | 1.11 | -8.61 |
| Total Points: | 59.00 | 58.37 | 0.63 |