| 9/5/2015 | South Dakota | 0 | at | Kansas State (6-7) | 34 | at B12 | ||
| 9/12/2015 | South Dakota | 27 | at | UC Davis (2-9) | 17 | at BSky | ||
| 9/19/2015 | Drake (5-6) | 0 | at | South Dakota | 52 | Pio | ||
| 10/3/2015 | Youngstown State (5-6,3-5) | 31 | at | South Dakota | 3 | |||
| 10/10/2015 | South Dakota | 21 | at | Western Illinois (7-6,5-4) | 40 | |||
| 10/17/2015 | South Dakota | 24 | at | North Dakota State (13-2,8-1) | 21 | |||
| 10/24/2015 | Missouri State (1-10,0-8) | 10 | at | South Dakota | 40 | |||
| 10/31/2015 | South Dakota | 7 | at | Northern Iowa (9-5,5-4) | 20 | |||
| 11/7/2015 | Southern Illinois (3-8,2-6) | 31 | at | South Dakota | 34 | |||
| 11/14/2015 | South Dakota State (8-4,5-3) | 30 | at | South Dakota | 23 | |||
| 11/21/2015 | South Dakota | 0 | at | Illinois State (10-3,8-1) | 46 |
| vs South Dakota | vs Other Opponents | South Dakota compared to OOs | |
| Record: | 6-5 | 63-61 | |
| Points Scored: | 25.45 | 28.16 | 2.71 |
| Points Allowed: | 21.00 | 27.10 | -6.10 |
| Margin: | 4.45 | 1.06 | -3.39 |
| Total Points: | 46.45 | 55.26 | -8.81 |