| 9/3/2015 | Northwest Missouri State | 31 | at | Nebraska-Kearney (0-11,0-11) | 0 | | | |
| 9/10/2015 | Missouri Southern (1-10,1-10) | 7 | at | Northwest Missouri State | 48 | | | |
| 9/19/2015 | Northwest Missouri State | 34 | at | Central Missouri (8-3,8-3) | 30 | | | |
| 9/26/2015 | Central Oklahoma (7-5,6-5) | 16 | at | Northwest Missouri State | 23 | | | |
| 10/3/2015 | Northwest Missouri State | 59 | at | Northeastern State (3-8,3-8) | 7 | | | |
| 10/10/2015 | Lindenwood (4-7,4-7) | 0 | at | Northwest Missouri State | 69 | | | |
| 10/17/2015 | Northwest Missouri State | 31 | at | Pittsburg State (6-5,6-5) | 14 | | | |
| 10/24/2015 | Fort Hays State (8-4,8-3) | 24 | at | Northwest Missouri State | 45 | | | |
| 10/31/2015 | Northwest Missouri State | 24 | at | Missouri Western (5-6,5-6) | 10 | | | |
| 11/7/2015 | Emporia State (11-3,9-3) | 10 | at | Northwest Missouri State | 44 | | | |
| 11/14/2015 | Northwest Missouri State | 49 | at | Washburn (5-6,5-6) | 13 | | | |
| 11/28/2015 | Humboldt State (10-2) | 7 | at | Northwest Missouri State | 54 | | NCAA D2 Championship - Second Round | GNWAC |
| 12/5/2015 | Emporia State (11-3,9-3) | 17 | at | Northwest Missouri State | 38 | | NCAA D2 Quarterfinal | |
| 12/12/2015 | West Georgia (12-2) | 23 | at | Northwest Missouri State | 38 | | NCAA D2 Semifinal | GSC |
| 12/19/2015 | Northwest Missouri State | 34 | vs | Shepherd (13-1) | 7 | | D2 Championship (Kamsas City KS) | vs MtnE |