| 9/3/2015 | Missouri Western (5-6,5-6) | 17 | at | Central Missouri | 18 | | | |
| 9/12/2015 | Central Missouri | 34 | at | Emporia State (11-3,9-3) | 45 | | | |
| 9/19/2015 | Northwest Missouri State (15-0,12-0) | 34 | at | Central Missouri | 30 | | | |
| 9/26/2015 | Central Missouri | 38 | at | Nebraska-Kearney (0-11,0-11) | 7 | | | |
| 10/3/2015 | Missouri Southern (1-10,1-10) | 10 | at | Central Missouri | 54 | | | |
| 10/10/2015 | Central Missouri | 38 | at | Washburn (5-6,5-6) | 28 | | | |
| 10/17/2015 | Central Missouri | 45 | at | Central Oklahoma (7-5,6-5) | 42 | | | |
| 10/24/2015 | Northeastern State (3-8,3-8) | 10 | at | Central Missouri | 54 | | | |
| 10/31/2015 | Central Missouri | 31 | at | Lindenwood (4-7,4-7) | 0 | | | |
| 11/7/2015 | Pittsburg State (6-5,6-5) | 6 | at | Central Missouri | 34 | | | |
| 11/14/2015 | Central Missouri | 14 | at | Fort Hays State (8-4,8-3) | 28 | | | |