| 9/3/2015 | Oklahoma State | 24 | at | Central Michigan (7-6) | 13 | at MAC | ||
| 9/12/2015 | Central Arkansas (7-4) | 8 | at | Oklahoma State | 32 | SLC (1AA) | ||
| 9/19/2015 | Texas-San Antonio (3-9) | 14 | at | Oklahoma State | 69 | CUSA | ||
| 9/26/2015 | Oklahoma State | 30 | at | Texas (5-7,4-5) | 27 | |||
| 10/3/2015 | Kansas State (6-7,3-6) | 34 | at | Oklahoma State | 36 | |||
| 10/10/2015 | Oklahoma State | 33 | at | West Virginia (8-5,4-5) | 26 | OT | ||
| 10/24/2015 | Kansas (0-12,0-9) | 10 | at | Oklahoma State | 58 | |||
| 10/31/2015 | Oklahoma State | 70 | at | Texas Tech (7-6,4-5) | 53 | |||
| 11/7/2015 | TCU (11-2,7-2) | 29 | at | Oklahoma State | 42 | |||
| 11/14/2015 | Oklahoma State | 35 | at | Iowa State (3-9,2-7) | 31 | |||
| 11/21/2015 | Baylor (10-3,6-3) | 45 | at | Oklahoma State | 35 | |||
| 11/28/2015 | Oklahoma (11-2,8-1) | 58 | at | Oklahoma State | 23 | |||
| 1/1/2016 | Oklahoma State | 20 | vs | Mississippi (10-3) | 48 | Sugar Bowl (New Orleans LA) | vs SEC |
| vs Oklahoma State | vs Other Opponents | Oklahoma State compared to OOs | |
| Record: | 3-10 | 85-65 | |
| Points Scored: | 30.46 | 33.37 | 2.91 |
| Points Allowed: | 39.00 | 29.08 | 9.92 |
| Margin: | -8.54 | 4.29 | 12.83 |
| Total Points: | 69.46 | 62.45 | 7.01 |