| 9/3/2015 | Cumberlands KY | 56 | at | Carson-Newman | 59 | MSC (NAIA) | ||
| Lenoir-Rhyne | 41 | at | West Chester | 28 | @ PSAC | |||
| 9/5/2015 | West Georgia | 44 | at | Catawba | 13 | GSC | ||
| Newberry | 31 | at | Florida Tech | 28 | @ GSC | |||
| Wingate | 14 | at | Johnson C Smith | 0 | @ CIAA | |||
| Brevard | 21 | at | Virginia Union | 35 | @ CIAA | |||
| Tusculum | 47 | at | Virginia-Wise | 28 | @ MtnE | |||
| Mars Hill | 14 | at | Western Carolina | 42 | @ SoCon (1AA) | |||
| 9/12/2015 | Bowie State | 35 | at | Brevard | 21 | CIAA | ||
| Shorter | 7 | at | Carson-Newman | 20 | GSC | |||
| Mars Hill | 34 | at | Chattanooga | 44 | @ SoCon (1AA) | |||
| Catawba | 35 | at | Davidson | 21 | @ Pio (1AA) | |||
| Jacksonville | 17 | at | Newberry | 14 | Pio (1AA) | |||
| Lenoir-Rhyne | 13 | at | North Greenville | 35 | @ D2Ind | |||
| Wingate | 30 | at | Shaw | 16 | @ CIAA | |||
| Virginia State | 40 | at | Tusculum | 13 | CIAA | |||
| 9/19/2015 | Catawba | 14 | at | Carson-Newman | 7 | |||
| Limestone | 26 | at | Mars Hill | 36 | D2Ind | |||
| North Greenville | 6 | at | Newberry | 31 | D2Ind | |||
| Lenoir-Rhyne | 55 | at | Tusculum | 52 | ||||
| Brevard | 0 | at | Wingate | 37 | ||||
| 9/26/2015 | Wingate | 17 | at | Catawba | 0 | |||
| Lenoir-Rhyne | 46 | at | Limestone | 22 | @ D2Ind | |||
| Carson-Newman | 62 | at | Mars Hill | 38 | ||||
| Tusculum | 31 | at | Newberry | 38 | ||||
| Brevard | 7 | at | Southern Utah | 55 | @ BSky (1AA) | |||
| 10/3/2015 | Tusculum | 20 | at | Brevard | 0 | |||
| Newberry | 13 | at | Catawba | 17 | ||||
| Carson-Newman | 17 | at | Lenoir-Rhyne | 52 | ||||
| North Greenville | 38 | at | Mars Hill | 14 | D2Ind | |||
| Limestone | 12 | at | Wingate | 17 | D2Ind | |||
| 10/10/2015 | Brevard | 14 | at | Carson-Newman | 45 | |||
| Catawba | 10 | at | Limestone | 3 | @ D2Ind | |||
| Mars Hill | 17 | at | Newberry | 14 | ||||
| Wingate | 17 | at | Tusculum | 26 | ||||
| 10/17/2015 | Limestone | 28 | at | Brevard | 25 | OT | D2Ind | |
| Newberry | 20 | at | Carson-Newman | 27 | ||||
| Mars Hill | 10 | at | Catawba | 29 | ||||
| Wingate | 24 | at | Lenoir-Rhyne | 14 | ||||
| Tusculum | 24 | at | North Greenville | 35 | @ D2Ind | |||
| 10/24/2015 | UNC Pembroke | 21 | at | Catawba | 39 | D2Ind | ||
| Tusculum | 45 | at | Limestone | 11 | @ D2Ind | |||
| Lenoir-Rhyne | 37 | at | Mars Hill | 41 | ||||
| Brevard | 7 | at | Newberry | 41 | ||||
| Carson-Newman | 41 | at | Wingate | 38 | OT | |||
| 10/31/2015 | Catawba | 29 | at | Brevard | 7 | |||
| Newberry | 52 | at | Lenoir-Rhyne | 14 | ||||
| Carson-Newman | 69 | at | Limestone | 28 | @ D2Ind | |||
| Mars Hill | 31 | at | Tusculum | 24 | ||||
| North Greenville | 27 | at | Wingate | 21 | D2Ind | |||
| 11/7/2015 | North Greenville | 45 | at | Carson-Newman | 48 | D2Ind | ||
| Brevard | 0 | at | Lenoir-Rhyne | 27 | ||||
| Wingate | 24 | at | Mars Hill | 42 | ||||
| Limestone | 7 | at | Newberry | 47 | D2Ind | |||
| Catawba | 24 | at | Tusculum | 6 | ||||
| 11/14/2015 | Mars Hill | 27 | at | Brevard | 7 | |||
| Tusculum | 32 | at | Carson-Newman | 65 | ||||
| Lenoir-Rhyne | 14 | at | Catawba | 28 | ||||
| Newberry | 26 | at | Wingate | 0 | ||||
| 11/21/2015 | Tuskegee | 26 | at | Catawba | 16 | NCAA D2 Championship - First Round | SIAC | |
| Newberry | 7 | at | North Alabama | 50 | NCAA D2 Championship - First Round | @ GSC | ||
| Carson-Newman | 59 | at | Valdosta State | 61 | NCAA D2 Championship - First Round | @ GSC |