| 9/4/2015 | Lehigh | 20 | at | Central Conn | 14 | Pat | ||
| 9/5/2015 | American Int'l | 3 | at | Bryant | 27 | NE10 (D2) | ||
| Kentucky Christian | 7 | at | Duquesne | 47 | MSC (NAIA) | |||
| Wagner | 16 | at | Rice | 56 | @ CUSA (1A) | |||
| Dayton | 27 | at | Robert Morris | 24 | Pio | |||
| Saint Anselm | 19 | at | Sacred Heart | 43 | NE10 (D2) | |||
| Georgetown | 20 | at | St Francis PA | 48 | Pat | |||
| 9/12/2015 | Duquesne | 26 | at | Bucknell | 7 | @ Pat | ||
| Central Conn | 9 | at | Stony Brook | 38 | @ CAAF | |||
| St Francis PA | 20 | at | Towson | 35 | @ CAAF | |||
| Sacred Heart | 56 | at | Valparaiso | 3 | @ Pio | |||
| Robert Morris | 14 | at | Youngstown State | 21 | OT | @ MVC | ||
| 9/19/2015 | Bryant | 20 | at | Brown | 16 | @ Ivy | ||
| Bowie State | 14 | at | Central Conn | 21 | CIAA (D2) | |||
| Duquesne | 13 | at | Dayton | 24 | @ Pio | |||
| Sacred Heart | 27 | at | Marist | 34 | @ Pio | |||
| Notre Dame OH | 24 | at | Robert Morris | 35 | MtnE (D2) | |||
| Monmouth NJ | 31 | at | Wagner | 16 | BigS | |||
| St Francis PA | 3 | at | Youngstown State | 48 | @ MVC | |||
| 9/26/2015 | Duquesne | 14 | at | Albany NY | 17 | @ CAAF | ||
| Bryant | 17 | at | Coastal Carolina | 31 | @ BigS | |||
| Sacred Heart | 7 | at | Dartmouth | 49 | @ Ivy | |||
| Central Conn | 14 | at | New Hampshire | 57 | @ CAAF | |||
| Robert Morris | 10 | at | South Dakota State | 34 | @ MVC | |||
| Lafayette | 35 | at | Wagner | 24 | Pat | |||
| 10/3/2015 | Central Conn | 10 | at | Duquesne | 27 | |||
| St Francis PA | 58 | at | East Tennessee St | 9 | @ IndFCS | |||
| Bryant | 24 | at | Monmouth NJ | 31 | @ BigS | |||
| Robert Morris | 9 | at | Wagner | 6 | ||||
| 10/10/2015 | Bryant | 33 | at | Central Conn | 35 | |||
| Wagner | 3 | at | Columbia | 26 | @ Ivy | |||
| Alderson-Broaddus | 18 | at | Duquesne | 53 | D2Ind (D2) | |||
| Sacred Heart | 26 | at | Robert Morris | 13 | ||||
| 10/17/2015 | Duquesne | 17 | at | Bryant | 38 | |||
| Dartmouth | 34 | at | Central Conn | 7 | Ivy | |||
| Cornell | 6 | at | Sacred Heart | 31 | Ivy | |||
| Wagner | 14 | at | St Francis PA | 43 | ||||
| 10/24/2015 | Wagner | 6 | at | BYU | 70 | @ Ind (1A) | ||
| St Francis PA | 24 | at | Bryant | 26 | ||||
| Duquesne | 16 | at | Robert Morris | 7 | ||||
| Central Conn | 26 | at | Sacred Heart | 10 | ||||
| 10/31/2015 | Robert Morris | 0 | at | Central Conn | 34 | |||
| Wagner | 17 | at | Duquesne | 35 | ||||
| Bryant | 33 | at | Holy Cross | 34 | @ Pat | |||
| Sacred Heart | 14 | at | St Francis PA | 23 | ||||
| 11/7/2015 | St Francis PA | 22 | at | Central Conn | 13 | |||
| East Tennessee St | 9 | at | Robert Morris | 21 | IndFCS | |||
| Duquesne | 41 | at | Sacred Heart | 14 | ||||
| Bryant | 40 | at | Wagner | 10 | ||||
| 11/14/2015 | Sacred Heart | 28 | at | Bryant | 19 | |||
| Robert Morris | 0 | at | St Francis PA | 21 | ||||
| Central Conn | 7 | at | Wagner | 28 | ||||
| 11/21/2015 | St Francis PA | 20 | at | Duquesne | 30 | |||
| Bryant | 20 | at | Robert Morris | 21 | ||||
| Wagner | 17 | at | Sacred Heart | 45 | ||||
| 11/28/2015 | Duquesne | 49 | at | William & Mary | 52 | FCS Playoff Round 1 | @ CAAF |