| 8/29/2015 | Webber International | 48 | at | Arizona Christian | 21 | Sun | ||
| Tabor | 45 | at | Lyon | 21 | KCAC | |||
| Southwestern | 5 | at | Wayland Baptist | 42 | KCAC | |||
| 9/5/2015 | Bacone | 3 | at | Lamar | 66 | @ SLC (1AA) | ||
| Lincoln MO | 35 | at | Langston | 32 | GLV (D2) | |||
| Lindsey Wilson | 76 | at | Lyon | 10 | MSC | |||
| Texas College | 6 | at | Mississippi College | 61 | @ GSC (D2) | |||
| Westminster MO | 17 | at | Southwestern Assemblies of God | 30 | UMWAC (D3) | |||
| Arizona Christian | 14 | at | Western New Mexico | 70 | @ RMAC (D2) | |||
| 9/11/2015 | Bacone | 0 | at | Texas Southern | 63 | @ SWAC (1AA) | ||
| 9/12/2015 | Southwestern Assemblies of God | 20 | at | Austin | 17 | @ SCAC (D3) | ||
| Langston | 33 | at | Bethany KS | 14 | @ KCAC | |||
| Lyon | 7 | at | Hendrix | 42 | @ SAA (D3) | |||
| Wayland Baptist | 44 | at | Howard Payne | 34 | @ ASWC (D3) | |||
| East Texas Baptist | 56 | at | Texas College | 14 | ASWC (D3) | |||
| 9/19/2015 | Bacone | 0 | vs | Angelo State | 56 | Arlington TX | vs LSC (D2) | |
| Wayland Baptist | 7 | at | Hardin-Simmons | 49 | @ ASWC (D3) | |||
| Langston | 35 | at | Panhandle State | 40 | @ D2Ind (D2) | |||
| Howard Payne | 24 | at | Southwestern Assemblies of God | 38 | ASWC (D3) | |||
| McMurry | 40 | at | Texas College | 0 | ASWC (D3) | |||
| 9/26/2015 | George Fox | 45 | at | Arizona Christian | 27 | NWC (D3) | ||
| Panhandle State | 69 | at | Bacone | 20 | D2Ind (D2) | |||
| McMurry | 29 | at | Langston | 32 | ASWC (D3) | |||
| Lyon | 10 | at | South Dakota Tech | 51 | @ GNWAC (D2) | |||
| Southwestern Assemblies of God | 28 | at | Texas Lutheran | 56 | @ SCAC (D3) | |||
| Sul Ross State | 54 | at | Wayland Baptist | 46 | ASWC (D3) | |||
| 10/3/2015 | Bacone | 37 | at | Lyon | 35 | |||
| Southwestern Assemblies of God | 49 | at | Texas College | 10 | ||||
| Arizona Christian | 36 | at | Wayland Baptist | 24 | ||||
| 10/10/2015 | Eastern New Mexico | 77 | at | Bacone | 14 | LSC (D2) | ||
| Arizona Christian | 55 | at | Langston | 52 | ||||
| Lyon | 7 | at | Southwestern Assemblies of God | 47 | ||||
| Texas College | 0 | at | Wayland Baptist | 24 | ||||
| 10/17/2015 | Lyon | 18 | at | Arizona Christian | 70 | |||
| Southwestern Assemblies of God | 20 | at | Langston | 23 | ||||
| Bacone | 20 | at | Texas College | 21 | ||||
| 10/24/2015 | Langston | 49 | at | Bacone | 7 | |||
| Austin | 28 | at | Lyon | 21 | OT | SCAC (D3) | ||
| Wayland Baptist | 14 | at | Southwestern Assemblies of God | 40 | ||||
| Arizona Christian | 26 | at | Texas College | 0 | ||||
| 10/31/2015 | Southwestern Assemblies of God | 30 | at | Arizona Christian | 61 | |||
| Langston | 48 | at | Lyon | 14 | ||||
| Texas College | 7 | at | Panhandle State | 62 | @ D2Ind (D2) | |||
| Bacone | 37 | at | Wayland Baptist | 30 | ||||
| 11/7/2015 | Arizona Christian | 27 | at | Bacone | 12 | |||
| Lyon | 14 | at | Texas College | 21 | ||||
| Langston | 48 | at | Wayland Baptist | 24 | ||||
| 11/14/2015 | Texas College | 0 | at | Langston | 50 | |||
| Wayland Baptist | 51 | at | Lyon | 30 | ||||
| Bacone | 26 | at | Southwestern Assemblies of God | 48 | ||||
| 11/21/2015 | Northwestern IA | 7 | at | Southwestern Assemblies of God | 10 | NCCAA Victory Bowl | GPAC |