| 8/25/2012 | William Penn | 39 | at | Iowa Wesleyan (3-8) | 14 | at None | ||
| 9/1/2012 | William Penn | 51 | at | Bethel KS (0-10) | 0 | at KCAC | ||
| 9/8/2012 | Luther (0-10) | 9 | at | William Penn | 31 | IIAC (D3) | ||
| 9/15/2012 | William Penn | 48 | at | Waldorf (4-7,1-6) | 14 | |||
| 9/29/2012 | Olivet Nazarene (3-8,2-8) | 3 | at | William Penn | 27 | |||
| 10/6/2012 | St Francis IL (6-5,4-4) | 8 | at | William Penn | 19 | |||
| 10/13/2012 | William Penn | 53 | at | St Mary KS (6-5) | 14 | at KCAC | ||
| 10/20/2012 | St Francis IN (9-3,5-3) | 28 | at | William Penn | 19 | |||
| 10/27/2012 | William Penn | 36 | at | Trinity International (4-7,2-6) | 25 | |||
| 11/3/2012 | Saint Ambrose (9-2,7-1) | 20 | at | William Penn | 17 | |||
| 11/10/2012 | Grand View (7-4,5-3) | 12 | at | William Penn | 17 | |||
| 11/17/2012 | William Penn | 0 | at | St Xavier (11-2,8-1) | 31 | NAIA playoffs |
| vs William Penn | vs Other Opponents | William Penn compared to OOs | |
| Record: | 3-9 | 59-62 | |
| Points Scored: | 14.83 | 27.79 | 12.96 |
| Points Allowed: | 29.75 | 27.85 | 1.90 |
| Margin: | -14.92 | -0.06 | 14.86 |
| Total Points: | 44.58 | 55.64 | -11.06 |