| 9/1/2012 | Briar Cliff (1-10,1-8) | 28 | at | Doane | 41 | |||
| 9/8/2012 | Dakota State (2-9) | 14 | at | Doane | 35 | NAIAInd | ||
| 9/15/2012 | Doane | 14 | at | Northwestern IA (9-3,7-2) | 28 | |||
| 9/22/2012 | Nebraska Wesleyan (6-4,5-4) | 24 | at | Doane | 38 | |||
| 9/29/2012 | Doane | 27 | at | Midland U. (4-6,3-6) | 7 | |||
| 10/6/2012 | Morningside (13-1,9-0) | 28 | at | Doane | 3 | |||
| 10/20/2012 | Doane | 24 | at | Dakota Wesleyan (6-4,5-4) | 28 | |||
| 10/27/2012 | Hastings (6-4,5-4) | 16 | at | Doane | 48 | |||
| 11/3/2012 | Doane | 55 | at | Dordt (1-10,0-9) | 6 | |||
| 11/10/2012 | Concordia NE (5-6,4-5) | 7 | at | Doane | 17 |
| vs Doane | vs Other Opponents | Doane compared to OOs | |
| Record: | 3-7 | 50-50 | |
| Points Scored: | 18.60 | 25.90 | 7.30 |
| Points Allowed: | 30.20 | 25.20 | 5.00 |
| Margin: | -11.60 | 0.70 | 12.30 |
| Total Points: | 48.80 | 51.10 | -2.30 |