| 8/25/2012 | Benedictine KS | 45 | at | Concordia NE | 37 | vs HAAC | ||
| 8/30/2012 | Valley City State | 7 | at | Morningside | 49 | vs NAIAInd | ||
| Southwestern | 0 | at | Northwestern IA | 49 | vs KCAC | |||
| 9/1/2012 | Dakota State | 14 | at | Dakota Wesleyan | 40 | vs NAIAInd | ||
| Briar Cliff | 28 | at | Doane | 41 | ||||
| St Mary KS | 20 | at | Nebraska Wesleyan | 25 | vs KCAC | |||
| Dordt | 7 | at | Waldorf | 43 | @ MSFA | |||
| 9/8/2012 | Graceland | 24 | at | Briar Cliff | 17 | vs HAAC | ||
| Dakota Wesleyan | 26 | at | Concordia NE | 23 | ||||
| Dakota State | 14 | at | Doane | 35 | vs NAIAInd | |||
| Hastings | 20 | at | Dordt | 7 | ||||
| Nebraska Wesleyan | 3 | at | Midland U. | 7 | ||||
| Northwestern IA | 7 | at | Morningside | 34 | ||||
| 9/15/2012 | Briar Cliff | 13 | at | Dakota Wesleyan | 24 | |||
| Concordia NE | 26 | at | Hastings | 34 | ||||
| Dordt | 7 | at | Midland U. | 26 | ||||
| Morningside | 35 | at | Nebraska Wesleyan | 10 | ||||
| Doane | 14 | at | Northwestern IA | 28 | ||||
| 9/22/2012 | Hastings | 34 | vs | Briar Cliff | 24 | Vermillion SD | ||
| Dordt | 12 | at | Concordia NE | 52 | ||||
| Nebraska Wesleyan | 24 | at | Doane | 38 | ||||
| Midland U. | 0 | at | Morningside | 42 | ||||
| Dakota State | 12 | at | Northwestern IA | 47 | vs NAIAInd | |||
| 9/29/2012 | Concordia NE | 28 | at | Dakota State | 7 | @ NAIAInd | ||
| Briar Cliff | 33 | at | Dordt | 29 | ||||
| Dakota Wesleyan | 30 | at | Hastings | 40 | ||||
| Doane | 27 | at | Midland U. | 7 | ||||
| Northwestern IA | 33 | at | Nebraska Wesleyan | 27 | ||||
| 10/6/2012 | Concordia NE | 45 | at | Briar Cliff | 12 | |||
| Hastings | 55 | at | Dakota State | 19 | @ NAIAInd | |||
| Dordt | 31 | at | Dakota Wesleyan | 45 | ||||
| Morningside | 28 | at | Doane | 3 | ||||
| Midland U. | 20 | at | Northwestern IA | 39 | ||||
| 10/13/2012 | Dakota State | 35 | at | Briar Cliff | 28 | vs NAIAInd | ||
| Northwestern IA | 16 | at | Concordia NE | 17 | ||||
| Nebraska Wesleyan | 27 | at | Dordt | 7 | ||||
| Hastings | 20 | at | Midland U. | 17 | ||||
| Dakota Wesleyan | 7 | at | Morningside | 63 | ||||
| 10/20/2012 | Doane | 24 | at | Dakota Wesleyan | 28 | |||
| Dakota State | 7 | at | Dordt | 24 | vs NAIAInd | |||
| Morningside | 53 | at | Hastings | 23 | ||||
| Midland U. | 40 | at | Mayville State | 20 | @ NAIAInd | |||
| Concordia NE | 6 | at | Nebraska Wesleyan | 16 | ||||
| Briar Cliff | 7 | at | Northwestern IA | 57 | ||||
| 10/27/2012 | Nebraska Wesleyan | 35 | at | Briar Cliff | 14 | |||
| Midland U. | 14 | at | Concordia NE | 23 | ||||
| Northwestern IA | 41 | at | Dakota Wesleyan | 13 | ||||
| Hastings | 16 | at | Doane | 48 | ||||
| Dordt | 0 | at | Morningside | 45 | ||||
| 11/3/2012 | Doane | 55 | at | Dordt | 6 | |||
| Northwestern IA | 45 | at | Hastings | 6 | ||||
| Briar Cliff | 20 | at | Midland U. | 28 | ||||
| Concordia NE | 0 | at | Morningside | 50 | ||||
| Dakota Wesleyan | 0 | at | Nebraska Wesleyan | 17 | ||||
| 11/10/2012 | Morningside | 62 | at | Briar Cliff | 0 | |||
| Midland U. | 14 | at | Dakota Wesleyan | 21 | ||||
| Concordia NE | 7 | at | Doane | 17 | ||||
| Nebraska Wesleyan | 21 | at | Hastings | 14 | ||||
| Dordt | 7 | at | Northwestern IA | 55 | ||||
| 11/17/2012 | Northwestern IA | 32 | at | Marian IN | 42 | NAIA playoffs | @ MSFA | |
| Montana Tech | 35 | at | Morningside | 40 | NAIA playoffs | vs Front | ||
| 11/24/2012 | Southern Oregon | 44 | at | Morningside | 47 | OT | NAIA Quarterfinals | vs Front |
| 12/1/2012 | St Xavier | 19 | at | Morningside | 47 | NAIA Semifinals | vs MSFA | |
| 12/13/2012 | Marian IN | 30 | vs | Morningside | 27 | OT | Rome Georgia - NAIA Championship | vs MSFA |