| 9/1/2012 | Mississippi College (2-8) | 17 | at | Millsaps | 23 | ASWC | ||
| 9/8/2012 | Millsaps | 54 | at | LaGrange (3-7) | 7 | at USASC | ||
| 9/15/2012 | Millsaps | 54 | at | Point (2-8) | 28 | at NAIAInd | ||
| 9/29/2012 | Millsaps | 33 | at | Centre (6-4,1-3) | 16 | |||
| 10/6/2012 | Huntingdon AL (6-3) | 45 | at | Millsaps | 24 | D3Ind | ||
| 10/13/2012 | Sewanee (3-7,1-3) | 28 | at | Millsaps | 42 | |||
| 10/20/2012 | Millsaps | 47 | at | Rhodes (6-3,2-2) | 13 | |||
| 10/27/2012 | Millsaps | 24 | at | Trinity TX (7-3) | 35 | at D3Ind | ||
| 11/3/2012 | Austin (2-8) | 34 | at | Millsaps | 36 | D3Ind | ||
| 11/10/2012 | Birmingham-Southern (7-3,3-1) | 35 | at | Millsaps | 21 |
| vs Millsaps | vs Other Opponents | Millsaps compared to OOs | |
| Record: | 3-7 | 41-47 | |
| Points Scored: | 25.80 | 24.17 | -1.63 |
| Points Allowed: | 35.80 | 26.58 | 9.22 |
| Margin: | -10.00 | -2.41 | 7.59 |
| Total Points: | 61.60 | 50.75 | 10.85 |