| 9/1/2012 | Wesley | 34 | at | East Texas Baptist (3-7) | 14 | at ASWC | ||
| 9/8/2012 | Wesley | 17 | at | Salisbury (9-3) | 7 | at E8 | ||
| 9/15/2012 | Mary Hardin-Baylor (13-1) | 32 | at | Wesley | 25 | ASWC | ||
| 9/22/2012 | Wesley | 25 | at | Louisiana College (8-3) | 22 | at ASWC | ||
| 10/6/2012 | Birmingham-Southern (7-3) | 17 | at | Wesley | 26 | SCAC | ||
| 10/13/2012 | Virginia U-Lynchburg (1-8) | 7 | at | Wesley | 24 | None (Unk?) | ||
| 10/20/2012 | Wesley | 30 | at | Menlo (3-6) | 13 | at NAIAInd | ||
| 10/27/2012 | Wesley | 31 | at | Huntingdon AL (6-3,0-1) | 21 | |||
| 11/3/2012 | Apprentice (0-8,0-1) | 0 | at | Wesley | 47 | |||
| 11/17/2012 | Mount Ida (8-3) | 14 | at | Wesley | 73 | Div 3 Playoffs 1st Round | ECFC | |
| 11/24/2012 | Cortland (9-2) | 6 | at | Wesley | 56 | D3 Playoffs Round 2 | NJAC | |
| 12/1/2012 | Wesley | 20 | at | Mary Hardin-Baylor (13-1) | 32 | D3 Quarterfinals | at ASWC |
| vs Wesley | vs Other Opponents | Wesley compared to OOs | |
| Record: | 2-10 | 76-38 | |
| Points Scored: | 15.42 | 35.18 | 19.76 |
| Points Allowed: | 34.00 | 23.54 | 10.46 |
| Margin: | -18.58 | 11.64 | 30.22 |
| Total Points: | 49.42 | 58.72 | -9.30 |