| 9/1/2012 | Concordia AL (4-4) | 20 | at | Mississippi Valley State | 19 | None (Unk?) | ||
| 9/8/2012 | Mississippi Valley State | 7 | at | Alabama State (7-4,7-2) | 29 | |||
| 9/13/2012 | Mississippi Valley State | 6 | at | Southern (4-7,3-6) | 0 | |||
| 9/22/2012 | Mississippi Valley State | 14 | at | Northwestern State (4-7) | 45 | at SLC | ||
| 10/6/2012 | Alabama A&M (7-4,6-3) | 35 | at | Mississippi Valley State | 0 | |||
| 10/13/2012 | Grambling (1-10,0-9) | 21 | at | Mississippi Valley State | 45 | |||
| 10/20/2012 | Mississippi Valley State | 7 | at | Jackson State (7-5,7-3) | 14 | OT | ||
| 10/27/2012 | Mississippi Valley State | 0 | at | Ark Pine Bluff (10-2,9-1) | 10 | |||
| 11/3/2012 | Alcorn State (4-7,4-5) | 9 | at | Mississippi Valley State | 33 | |||
| 11/10/2012 | Prairie View (3-8,3-6) | 20 | at | Mississippi Valley State | 22 | |||
| 11/17/2012 | Mississippi Valley State | 34 | at | Texas Southern (2-9,2-7) | 3 |
| vs Mississippi Valley State | vs Other Opponents | Mississippi Valley State compared to OOs | |
| Record: | 6-5 | 47-62 | |
| Points Scored: | 18.73 | 23.89 | 5.16 |
| Points Allowed: | 17.00 | 29.64 | -12.64 |
| Margin: | 1.73 | -5.75 | -7.48 |
| Total Points: | 35.73 | 53.53 | -17.80 |