| 9/1/2012 | Colorado State (4-8) | 22 | vs | Colorado | 17 | Denver CO | MW | |
| 9/8/2012 | Sacramento State (6-5) | 30 | at | Colorado | 28 | BSky (1AA) | ||
| 9/15/2012 | Colorado | 14 | at | Fresno State (9-4) | 69 | at MW | ||
| 9/22/2012 | Colorado | 35 | at | Washington State (3-9,1-8) | 34 | |||
| 9/29/2012 | UCLA (9-5,6-4) | 42 | at | Colorado | 14 | |||
| 10/11/2012 | Arizona State (8-5,5-4) | 51 | at | Colorado | 17 | |||
| 10/20/2012 | Colorado | 6 | at | Southern California (7-6,5-4) | 50 | |||
| 10/27/2012 | Colorado | 14 | at | Oregon (12-1,8-1) | 70 | |||
| 11/3/2012 | Stanford (12-2,9-1) | 48 | at | Colorado | 0 | |||
| 11/10/2012 | Colorado | 31 | at | Arizona (8-5,4-5) | 56 | |||
| 11/17/2012 | Washington (7-6,5-4) | 38 | at | Colorado | 3 | |||
| 11/23/2012 | Utah (5-7,3-6) | 42 | at | Colorado | 35 |
| vs Colorado | vs Other Opponents | Colorado compared to OOs | |
| Record: | 11-1 | 79-62 | |
| Points Scored: | 46.00 | 30.48 | -15.52 |
| Points Allowed: | 17.83 | 26.86 | -9.03 |
| Margin: | 28.17 | 3.62 | -24.55 |
| Total Points: | 63.83 | 57.34 | 6.49 |