| 9/3/2011 | Tennessee Tech Golden Eagles 7 @ Iowa 34 | |
| 9/10/2011 | Iowa 41 @ Iowa State Cyclones 44 3OT | |
| 9/17/2011 | Pittsburgh Panthers 27 @ Iowa 31 | |
| 9/24/2011 | UL Monroe Warhawks 17 @ Iowa 45 | |
| 10/8/2011 | Iowa 3 @ Penn State Nittany Lions 13 | † |
| 10/15/2011 | Northwestern Wildcats 31 @ Iowa 41 | † |
| 10/22/2011 | Indiana Hoosiers 24 @ Iowa 45 | † |
| 10/29/2011 | Iowa 21 @ Minnesota Golden Gophers 22 | † |
| 11/5/2011 | Michigan Wolverines 16 @ Iowa 24 | † |
| 11/12/2011 | Michigan State Spartans 37 @ Iowa 21 | † |
| 11/19/2011 | Iowa 31 @ Purdue Boilermakers 21 | † |
| 11/25/2011 | Iowa 7 @ Nebraska Cornhuskers 20 | † |
| 12/30/2011 | Iowa 14 vs Oklahoma Sooners 31 ( Insight Bowl ) |