| 9/5/2009 | Colorado St-Pueblo 28 @ NW Oklahoma St 34 | |
| 9/12/2009 | Black Hills St 21 @ NW Oklahoma St 7 | |
| 9/19/2009 | NW Oklahoma St 41 @ SW Assem of God 16 | † |
| 9/26/2009 | NW Oklahoma St 9 @ SE Oklahoma St 29 | |
| 10/10/2009 | Langston 21 @ NW Oklahoma St 27 | † |
| 10/17/2009 | NW Oklahoma St 28 @ Missouri S&T 31 | |
| 10/24/2009 | Bacone 9 @ NW Oklahoma St 64 | † |
| 10/31/2009 | NW Oklahoma St 48 @ Southern Nazarene 28 | † |
| 11/7/2009 | Texas College 24 @ NW Oklahoma St 71 | † |
| 11/14/2009 | NW Oklahoma St 68 @ Panhandle St 28 |