| 8/29/2009 | Panhandle St 13 @ Fort Lewis 23 | |
| 9/5/2009 | Panhandle St 7 @ Truman St 54 | |
| 9/19/2009 | Langston 27 vs Panhandle St 21 (Guymon OK) | |
| 9/26/2009 | Panhandle St 50 @ SW Assem of God 58 | |
| 10/3/2009 | Incarnate Word 38 @ Panhandle St 35 1OT | † |
| 10/10/2009 | Southwestern-KS 14 @ Panhandle St 35 | |
| 10/17/2009 | Bacone 38 @ Panhandle St 69 | |
| 10/24/2009 | Panhandle St 31 @ Texas College 26 | |
| 10/31/2009 | Panhandle St 28 @ SW Oklahoma St 24 | |
| 11/7/2009 | Panhandle St 20 @ Southern Nazarene 48 | |
| 11/14/2009 | NW Oklahoma St 68 @ Panhandle St 28 |