| 9/5/2009 | Franklin & Marshall 29 @ Washington and Lee 27 | |
| 9/12/2009 | Catholic 21 @ Franklin & Marshall 42 | |
| 9/19/2009 | Dickinson 45 @ Franklin & Marshall 43 | † |
| 9/26/2009 | Franklin & Marshall 34 @ Juniata 7 | † |
| 10/10/2009 | Franklin & Marshall 21 @ Ursinus 14 | † |
| 10/17/2009 | Moravian 13 @ Franklin & Marshall 29 | † |
| 10/24/2009 | Muhlenberg 7 @ Franklin & Marshall 20 | † |
| 10/31/2009 | Franklin & Marshall 41 @ McDaniel 20 | † |
| 11/7/2009 | Franklin & Marshall 13 @ Johns Hopkins 51 | † |
| 11/14/2009 | Gettysburg 23 @ Franklin & Marshall 33 | † |
| 11/21/2009 | Wilkes 24 @ Franklin & Marshall 29 (D3) |