| 8/27/2009 | Northern St SD 14 @ Missouri Western 49 | |
| 9/5/2009 | Missouri Western 35 @ Mesa St 14 | |
| 9/12/2009 | Missouri Western 58 @ Fort Hays St 31 | † |
| 9/19/2009 | Washburn 34 @ Missouri Western 37 | † |
| 9/26/2009 | Missouri Western 45 @ Pittsburg St 40 | † |
| 10/3/2009 | NW Missouri St 49 @ Missouri Western 35 | † |
| 10/10/2009 | Missouri Western 38 @ Truman St 14 | † |
| 10/17/2009 | Central Missouri 21 @ Missouri Western 36 | † |
| 10/24/2009 | Missouri Southern 35 @ Missouri Western 34 | † |
| 10/31/2009 | Missouri Western 29 @ Emporia St 6 | † |
| 11/7/2009 | Nebraska-Omaha 30 @ Missouri Western 21 | † |
| 12/5/2009 | Augustana IL 21 @ Missouri Western 34 |