| 9/3/2009 | Western Illinois 35 @ Sam Houston 28 | |
| 9/12/2009 | N Dakota St 45 @ Sam Houston 48 | |
| 9/26/2009 | Sam Houston 3 @ Tulsa 56 | |
| 10/3/2009 | St Joseph's 0 @ Sam Houston 41 | |
| 10/10/2009 | Nicholls St 21 @ Sam Houston 44 | † |
| 10/17/2009 | Sam Houston 21 @ SE Louisiana 37 | † |
| 10/24/2009 | Sam Houston 3 @ SF Austin 42 | † |
| 10/31/2009 | Northwestern St 30 @ Sam Houston 34 | † |
| 11/7/2009 | Sam Houston 42 @ McNeese St 63 | † |
| 11/14/2009 | Central Arkansas 14 @ Sam Houston 17 | † |
| 11/21/2009 | Sam Houston 20 @ Texas St 28 | † |