| 9/5/2009 | Southern Illinois 28 @ Marshall 31 | |
| 9/12/2009 | Marshall 10 @ Virginia Tech 52 | |
| 9/19/2009 | Bowling Green 10 @ Marshall 17 | |
| 9/26/2009 | Marshall 27 @ Memphis 16 | † |
| 10/3/2009 | East Carolina 21 @ Marshall 17 | † |
| 10/10/2009 | Marshall 31 @ Tulane 10 | † |
| 10/17/2009 | Marshall 7 @ West Virginia 24 | |
| 10/24/2009 | UAB 7 @ Marshall 27 | † |
| 11/1/2009 | Marshall 20 @ UCF 21 | † |
| 11/14/2009 | Southern Miss 27 @ Marshall 20 | † |
| 11/21/2009 | SMU 31 @ Marshall 34 | † |
| 11/28/2009 | Marshall 21 @ UTEP 52 | † |
| 12/26/2009 | Ohio 17 vs Marshall 21 (Little Ceasar's Pizza Bowl) |