| 9/5/2009 | Central Michigan 6 @ Arizona 19 | |
| 9/12/2009 | Central Michigan 29 @ Michigan St 27 | |
| 9/19/2009 | Alcorn St 0 @ Central Michigan 48 | |
| 9/26/2009 | Akron 21 @ Central Michigan 48 | † |
| 10/3/2009 | Central Michigan 20 @ Buffalo 13 | † |
| 10/10/2009 | Eastern Michigan 8 @ Central Michigan 56 | † |
| 10/17/2009 | Central Michigan 34 @ Western Michigan 23 | † |
| 10/24/2009 | Central Michigan 24 @ Bowling Green 10 | † |
| 10/31/2009 | Central Michigan 10 @ Boston College 31 | |
| 11/11/2009 | Toledo 28 @ Central Michigan 56 | † |
| 11/18/2009 | Central Michigan 35 @ Ball State 3 | † |
| 11/27/2009 | Northern Illinois 31 @ Central Michigan 45 | † |
| 12/4/2009 | Ohio 10 vs Central Michigan 20 (MAC CG) | † |
| 1/6/2010 | Troy 41 vs Central Michigan 44 2OT (GMAC Bowl) |