| 9/5/2009 | Grand View NAIA | 0 | @ | Drake | 22 | ||||
| 9/12/2009 | Drake | 34 | @ | Marist | 6 | Pio | |||
| 9/19/2009 | Drake | 21 | @ | South Dakota | 51 | ||||
| 10/3/2009 | Valparaiso | 14 | @ | Drake | 34 | Pio | |||
| 10/10/2009 | Missouri S&T D2 | 0 | @ | Drake | 19 | ||||
| 10/17/2009 | Drake | 21 | @ | San Diego | 14 | Pio | |||
| 10/24/2009 | Drake | 21 | @ | Davidson | 16 | Pio | |||
| 10/31/2009 | Jacksonville | 38 | @ | Drake | 45 | Pio | |||
| 11/7/2009 | Campbell | 6 | @ | Drake | 49 | Pio | |||
| 11/14/2009 | Dayton | 23 | @ | Drake | 6 | Pio | |||
| 11/21/2009 | Drake | 17 | @ | Butler | 20 | Pio |