| Thursday, 28 Aug 2008 | |||||||
| Northeastern St OK (D2) | 3 | @ | Arkansas Tech (D2) | 22 | |||
| NCC | St Cloud St (D2) | 10 | @ | Augustana SD (D2) | 13 | ||
| Northeastern | 14 | @ | Ball St | 48 | |||
| #24 Wake Forest | 41 | @ | Baylor | 13 | |||
| UTEP | 17 | @ | Buffalo | 42 | |||
| Henderson St (D2) | 14 | @ | Central Arkansas | 38 | |||
| Eastern Illinois | 12 | @ | Central Michigan | 31 | |||
| Minn St-Mankato (D2) | 9 | @ | Central Missouri (D2) | 29 | |||
| Eastern Kentucky | 7 | @ | Cincinnati | 40 | |||
| Fairmont St (D2) | 23 | @ | Clarion (D2) | 20 | |||
| Carson-Newman (D2) | 77 | @ | Concord (D2) | 14 | |||
| Hofstra | 3 | @ | Connecticut | 35 | |||
| Upper Iowa (D2) | 13 | @ | Drake | 17 | |||
| Virginia Union (D2) | 11 | @ | East Stroudsburg (D2) | 14 | |||
| Indiana St | 0 | @ | Eastern Michigan | 52 | |||
| RMAC | New Mexico Highlands (D2) | 0 | @ | Fort Hays St (D2) | 44 | ||
| Jacksonville St | 14 | @ | Georgia Tech | 41 | |||
| South Dakota St | 17 | @ | Iowa St | 44 | |||
| Virginia-Wise (NAIA) | 56 | vs | Kentucky Christian (NAIA) | 12 | Morehead KY | ||
| Indianapolis (D2) | 40 | @ | Kentucky Wesleyan (D2) | 14 | |||
| St Anselm (D2) | 0 | @ | Kutztown (D2) | 35 | |||
| Gannon (D2) | 24 | @ | Lake Erie (D2) | 22 | |||
| Glenville St (D2) | 30 | @ | Lock Haven (D2) | 0 | |||
| Chadron St (D2) | 37 | @ | Mary (D2) | 17 | |||
| West Texas A&M (D2) | 23 | @ | Mesa St (D2) | 20 | |||
| Charleston Southern | 7 | @ | Miami FL | 42 | |||
| Vanderbilt | 34 | @ | Miami OH | 13 | |||
| SBC | Troy | 31 | @ | Middle Tennessee St | 17 | ||
| Bemidji St (D2) | 27 | @ | Minot St (NAIA) | 24 | |||
| Southern Oregon (NAIA) | 30 | @ | Montana Tech (NAIA) | 25 | |||
| Lambuth (NAIA) | 17 | @ | Murray St | 41 | |||
| GSC | Southern Arkansas (D2) | 14 | @ | North Alabama (D2) | 57 | ||
| TAMU-Kingsville (D2) | 14 | @ | North Dakota (D2) | 40 | |||
| Austin Peay | 6 | @ | North Dakota St | 41 | |||
| Missouri Western (D2) | 38 | @ | Northern St SD (D2) | 27 | |||
| SW Oklahoma St (D2) | 29 | @ | NW Oklahoma St (NAIA) | 15 | |||
| East Central OK (D2) | 14 | @ | Sam Houston St | 58 | |||
| West Georgia (D2) | 19 | @ | Samford | 21 | |||
| SW Baptist (D2) | 28 | @ | SE Missouri St | 35 | OT | ||
| North Carolina St | 0 | @ | #25 South Carolina | 34 | |||
| P10 | Oregon St | 28 | @ | Stanford | 36 | ||
| LSC | SE Oklahoma St (D2) | 10 | @ | Tarleton St (D2) | 51 | ||
| Gardner-Webb | 12 | @ | Tennessee Tech | 28 | |||
| Colorado Mines (D2) | 3 | @ | Washburn (D2) | 27 | |||
| Montana-Western (NAIA) | 6 | @ | Weber St | 62 | |||
| Shorter (NAIA) | 0 | @ | Western Carolina | 35 | |||
| Friday, 29 Aug 2008 | |||||||
| Temple | 35 | @ | Army | 7 | |||
| Millersville (D2) | 22 | @ | Bentley (D2) | 35 | |||
| CUSA | SMU | 27 | @ | Rice | 56 | ||
| Marist | 22 | @ | San Diego | 40 | |||
| Saturday, 30 Aug 2008 | |||||||
| Southern Utah | 7 | @ | Air Force | 41 | |||
| Tennessee St | 34 | @ | Alabama A&M | 13 | |||
| CUSA | Tulsa | 45 | @ | Alabama-Birmingham | 22 | ||
| Shaw (D2) | 10 | @ | Albany St GA (D2) | 27 | |||
| SE Louisiana St | 34 | @ | Alcorn St | 28 | |||
| Idaho | 0 | @ | Arizona | 70 | |||
| Northern Arizona | 13 | @ | #23 Arizona St | 30 | |||
| Western Illinois | 24 | @ | Arkansas | 28 | |||
| Arkansas-Monticello (D2) | 21 | @ | Arkansas-Pine Bluff | 7 | |||
| Bloomsburg (D2) | 49 | @ | Ashland (D2) | 42 | |||
| Louisiana-Monroe | 0 | @ | #14 Auburn | 34 | |||
| Carroll MT (NAIA) | 41 | @ | Azusa Pacific (NAIA) | 22 | |||
| SIAC | Morehouse (D2) | 3 | @ | Benedict (D2) | 7 | ||
| Idaho St | 7 | @ | Boise St | 49 | |||
| D2Ind | UNC Pembroke (D2) | 28 | @ | Brevard (D2) | 0 | ||
| Northern Iowa | 17 | @ | #17 Brigham Young | 41 | |||
| NE10 | American Int'l (D2) | 45 | @ | C.W. Post (D2) | 19 | ||
| Michigan St | 31 | @ | California | 38 | |||
| PSAC | West Chester (D2) | 32 | @ | California PA (D2) | 44 | ||
| Birmingham-Southern (D3) | 12 | @ | Campbell | 6 | |||
| MSC | Cumberland TN (NAIA) | 48 | @ | Campbellsville (NAIA) | 38 | ||
| St Augustine's (D2) | 14 | @ | Catawba (D2) | 7 | |||
| Bryant (D2) | 35 | @ | Central Conn St | 42 | |||
| South Carolina St | 0 | @ | Central Florida | 17 | |||
| Pittsburg St (D2) | 16 | @ | Central Oklahoma (D2) | 12 | |||
| Bowie St (D2) | 51 | @ | Cheyney (D2) | 26 | |||
| SIAC | Fort Valley St (D2) | 24 | @ | Clark Atlanta (D2) | 19 | ||
| #16 Alabama | 34 | vs | Clemson | 10 | Atlanta GA | ||
| Minnesota-Duluth (D2) | 40 | @ | Concordia-St Paul (D2) | 0 | |||
| Bacone (NAIA) | 34 | @ | Dakota St (NAIA) | 27 | |||
| Rocky Mountain (NAIA) | 34 | @ | Dickinson St (NAIA) | 19 | |||
| Central Washington (D2) | 44 | @ | Dixie St (D2) | 38 | |||
| James Madison | 7 | @ | Duke | 31 | |||
| Virginia Tech | 22 | vs | East Carolina | 27 | Charlotte NC | ||
| Chowan (D2) | 3 | @ | Elizabeth City St (D2) | 55 | |||
| Richmond | 28 | @ | Elon | 10 | |||
| Western St CO (D2) | 0 | @ | Emporia St (D2) | 42 | |||
| Hawaii | 10 | @ | #3 Florida | 56 | |||
| Alabama St | 20 | @ | Florida A&M | 30 | |||
| Mars Hill (D2) | 14 | @ | Furman | 62 | |||
| Georgia Southern | 21 | @ | #9 Georgia | 45 | |||
| Briar Cliff (NAIA) | 17 | @ | Grand View (NAIA) | 20 | |||
| St Joseph's IN (D2) | 6 | @ | Hillsdale (D2) | 49 | |||
| Southern U. | 3 | @ | Houston | 55 | |||
| Western Kentucky | 13 | @ | Indiana | 31 | |||
| Maine | 3 | @ | Iowa | 46 | |||
| Florida Int'l | 10 | @ | #11 Kansas | 40 | |||
| North Texas | 6 | @ | Kansas St | 45 | |||
| Boston College | 21 | vs | Kent St | 0 | Cleveland OH | ||
| SIAC | Lane (D2) | 32 | @ | Kentucky St (D2) | 16 | ||
| West Virginia Tech (D2) | 13 | @ | Lenoir-Rhyne (D2) | 51 | |||
| North Greenville (D2) | 10 | @ | Liberty | 49 | |||
| Concordia AL (NAIA) | 26 | vs | Livingstone (D2) | 21 | Greenville SC | ||
| Mississippi St | 14 | @ | Louisiana Tech | 22 | |||
| Appalachian St | 13 | @ | #6 LSU | 41 | |||
| MSFA | Ohio Dominican (NAIA) | 70 | @ | Marian (NAIA) | 7 | ||
| Illinois St | 10 | @ | Marshall | 35 | |||
| Delaware | 7 | @ | Maryland | 14 | |||
| Albany NY | 16 | @ | Massachusetts | 28 | |||
| #22 Utah | 25 | @ | Michigan | 23 | |||
| Winona St (D2) | 21 | @ | Michigan Tech (D2) | 26 | |||
| Northern Illinois | 27 | @ | Minnesota | 31 | |||
| Memphis | 24 | @ | Mississippi | 41 | |||
| Texas College (NAIA) | 0 | @ | Mississippi Valley St | 38 | |||
| Illinois | 42 | @ | #6 Missouri | 52 | |||
| Harding (D2) | 31 | @ | Missouri Southern (D2) | 45 | |||
| Adams St (D2) | 3 | @ | Montana St | 59 | |||
| Southern Virginia (NAIA) | 6 | @ | Morehead St | 49 | |||
| Towson | 13 | @ | Navy | 41 | |||
| Western Michigan | 24 | @ | Nebraska | 47 | |||
| Wayne St NE (D2) | 28 | @ | Nebraska-Kearney (D2) | 12 | |||
| Grambling St | 13 | @ | Nevada | 49 | |||
| MW | #25 TCU | 26 | @ | New Mexico | 3 | ||
| Valdosta St (D2) | 14 | @ | Newberry (D2) | 9 | |||
| Virginia St (D2) | 7 | @ | Norfolk St | 47 | |||
| McNeese St | 27 | @ | North Carolina | 35 | |||
| Johnson C. Smith (D2) | 12 | @ | North Carolina A&T | 44 | |||
| Syracuse | 10 | @ | Northwestern | 30 | |||
| TAMU-Commerce (D2) | 14 | @ | Northwestern St | 30 | |||
| Abilene Christian (D2) | 44 | @ | NW Missouri St (D2) | 27 | |||
| Youngstown St | 0 | @ | #4 Ohio State | 43 | |||
| Fort Lewis (D2) | 21 | @ | OK Panhandle St (D2) | 0 | |||
| Chattanooga | 2 | @ | #6 Oklahoma | 57 | |||
| P10 | Washington | 10 | @ | #8 Oregon | 44 | ||
| Coastal Carolina | 10 | @ | #20 Penn State | 66 | |||
| Hastings (NAIA) | 26 | @ | Peru St (NAIA) | 0 | |||
| Bowling Green | 27 | @ | Pittsburgh | 17 | |||
| Western Oregon (D2) | 14 | @ | Portland St | 31 | |||
| Monmouth NJ | 24 | @ | Rhode Island | 27 | |||
| Humboldt St (D2) | 13 | @ | Sacramento St | 45 | |||
| Assumption (D2) | 21 | @ | Sacred Heart | 42 | |||
| Cal Poly SLO | 29 | @ | San Diego St | 27 | |||
| UC-Davis | 10 | @ | San Jose St | 13 | |||
| Jacksonville FL | 20 | @ | Savannah St | 7 | |||
| Slippery Rock (D2) | 20 | @ | Seton Hill (NAIA) | 27 | |||
| Shepherd (D2) | 20 | @ | Shippensburg (D2) | 16 | |||
| St Ambrose (NAIA) | 0 | @ | South Dakota | 52 | |||
| Haskell (NAIA) | 7 | @ | South Dakota Tech (NAIA) | 62 | |||
| Tennessee-Martin | 7 | @ | #19 South Florida | 56 | |||
| Louisiana-Lafayette | 21 | @ | Southern Miss | 51 | |||
| Eastern New Mexico (D2) | 9 | @ | Southern Nazarene (NAIA) | 16 | |||
| Wingate (D2) | 34 | @ | St Paul's (D2) | 10 | |||
| Langston (D2) | 19 | @ | Stephen F. Austin | 56 | |||
| Colgate | 26 | @ | Stony Brook | 42 | |||
| NSIC | Minnesota-Crookston (D2) | 14 | @ | SW Minnesota St (D2) | 54 | ||
| Florida Atlantic | 10 | @ | #10 Texas | 52 | |||
| Arkansas St | 18 | @ | Texas A&M | 14 | |||
| SWAC | Prairie View A&M | 34 | @ | Texas Southern | 14 | ||
| Angelo St (D2) | 14 | @ | Texas St-San Marcos | 21 | |||
| Eastern Washington | 24 | @ | #21 Texas Tech | 49 | |||
| Webber Int'l (NAIA) | 7 | @ | The Citadel | 54 | |||
| Ferris St (D2) | 14 | @ | Tiffin (D2) | 12 | |||
| MSFA | Walsh (NAIA) | 31 | @ | Trinity Int'l (NAIA) | 7 | ||
| Charleston WV (D2) | 0 | @ | Tusculum (D2) | 40 | |||
| Utah St | 17 | @ | UNLV | 27 | |||
| Findlay (D2) | 26 | @ | Urbana (NAIA) | 0 | |||
| Minn St-Moorhead (D3) | 29 | @ | Valley City St (NAIA) | 30 | |||
| #1 Southern Cal | 52 | @ | Virginia | 7 | |||
| #23 Oklahoma St | 39 | vs | Washington St | 13 | Seattle WA | ||
| GLIAC | Mercyhurst (D2) | 10 | @ | Wayne St MI (D2) | 14 | ||
| Belhaven (NAIA) | 12 | @ | West Alabama (D2) | 49 | |||
| Edinboro (D2) | 35 | @ | West Liberty St (D2) | 10 | |||
| Villanova | 21 | @ | #7 West Virginia | 48 | |||
| Lincoln MO (D2) | 13 | @ | West Virginia St (D2) | 67 | |||
| Doane (NAIA) | 15 | vs | William Jewell (NAIA) | 12 | Platte City MO | ||
| Waldorf (NAIA) | 3 | @ | William Penn (NAIA) | 41 | |||
| Akron | 17 | @ | Wisconsin | 38 | |||
| Presbyterian | 21 | @ | Wofford | 38 | |||
| Southern Conn St (D2) | 26 | @ | WV Wesleyan (D2) | 21 | |||
| Ohio U. | 20 | @ | Wyoming | 21 | |||
| Sunday, 31 Aug 2008 | |||||||
| Colorado St | 17 | vs | Colorado | 38 | Denver CO | ||
| Central St OH (D2) | 12 | @ | Dayton | 31 | |||
| Hampton | 17 | vs | Jackson St | 13 | Orlando FL | ||
| #22 Kentucky | 27 | @ | Louisville | 2 | |||
| Stillman (D2) | 38 | vs | Miles (D2) | 12 | Birmingham AL | ||
| Fayetteville St (D2) | 33 | @ | North Carolina Central | 22 | |||
| Monday, 1 Sep 2008 | |||||||
| Fresno St | 24 | @ | Rutgers | 7 | |||
| Tennessee | 24 | @ | UCLA | 27 | OT | ||