| 9/2/2006 | SE Missouri St | 38 | @ | Austin Peay | 13 | ||||
| 9/9/2006 | Missouri-Rolla D2 | 23 | @ | SE Missouri St | 44 | ||||
| 9/16/2006 | SE Missouri St | 7 | @ | Jacksonville St | 38 | OVC | |||
| 9/30/2006 | Samford | 14 | @ | SE Missouri St | 19 | OVC | |||
| 10/7/2006 | SE Missouri St | 0 | @ | Eastern Illinois | 21 | OVC | |||
| 10/14/2006 | SE Missouri St | 7 | @ | #12 Arkansas | 63 | ||||
| 10/21/2006 | Eastern Kentucky | 27 | @ | SE Missouri St | 21 | OVC | |||
| 10/28/2006 | SE Missouri St | 24 | @ | Murray St | 17 | OVC | |||
| 11/4/2006 | Tennessee-Martin | 28 | @ | SE Missouri St | 14 | OVC | |||
| 11/11/2006 | SE Missouri St | 0 | @ | Tennessee St | 31 | OVC | |||
| 11/18/2006 | Tennessee Tech | 32 | @ | SE Missouri St | 29 | OVC |