| 9/3/2005 | Charleston So | 14 | @ | The Citadel | 28 | ||||
| 9/10/2005 | Presbyterian | 42 | @ | Charleston So | 0 | ||||
| 9/17/2005 | Jacksonville | 10 | @ | Charleston So | 16 | ||||
| 9/24/2005 | Charleston So | 35 | @ | North Greenville | 28 | ||||
| 10/1/2005 | Howard | 27 | @ | Charleston So | 22 | ||||
| 10/8/2005 | Charleston So | 12 | @ | VMI | 34 | BigS | |||
| 10/15/2005 | WV Wesleyan | 42 | @ | Charleston So | 63 | ||||
| 10/22/2005 | Savannah St | 28 | @ | Charleston So | 48 | ||||
| 11/5/2005 | Charleston So | 38 | @ | Gardner Webb | 7 | BigS | |||
| 11/12/2005 | Liberty | 30 | @ | Charleston So | 31 | BigS | |||
| 11/19/2005 | Coastal Car | 27 | @ | Charleston So | 34 | 2 OT | BigS |