| 9/1/2005 | UCF | 15 | @ | South Carolina | 24 | ||||
| 9/10/2005 | South Carolina | 15 | @ | #8 Georgia | 17 | SEC | |||
| 9/17/2005 | #13 Alabama | 37 | @ | South Carolina | 14 | SEC | |||
| 9/24/2005 | Troy | 20 | @ | South Carolina | 45 | ||||
| 10/1/2005 | South Carolina | 7 | @ | #7 Auburn | 48 | SEC | |||
| 10/8/2005 | Kentucky | 16 | @ | South Carolina | 44 | SEC | |||
| 10/22/2005 | Vanderbilt | 28 | @ | South Carolina | 35 | SEC | |||
| 10/29/2005 | South Carolina | 16 | @ | Tennessee | 15 | SEC | |||
| 11/5/2005 | South Carolina | 14 | @ | Arkansas | 10 | SEC | |||
| 11/12/2005 | #16 Florida | 22 | @ | South Carolina | 30 | SEC | |||
| 11/19/2005 | #23 Clemson | 13 | @ | South Carolina | 9 | ||||
| 12/30/2005 | Missouri | 38 | vs | South Carolina | 31 | Independence |