| 9/2/2023 | Alcorn State (7-4) | 14 | at | Southern Miss | 40 | SWAC (1AA) | ||
| 9/9/2023 | Southern Miss | 13 | at | Florida State (13-1) | 66 | at ACC | ||
| 9/16/2023 | Tulane (11-3) | 21 | at | Southern Miss | 3 | AAC | ||
| 9/23/2023 | Southern Miss | 37 | at | Arkansas State (6-7,4-4) | 44 | |||
| 9/30/2023 | Texas State (8-5,4-4) | 50 | at | Southern Miss | 36 | |||
| 10/7/2023 | Old Dominion (6-7,5-3) | 17 | at | Southern Miss | 13 | |||
| 10/17/2023 | Southern Miss | 3 | at | South Alabama (7-6,4-4) | 55 | |||
| 10/28/2023 | Southern Miss | 38 | at | Appalachian State (9-5,6-3) | 48 | |||
| 11/4/2023 | UL Monroe (2-10,0-8) | 7 | at | Southern Miss | 24 | |||
| 11/9/2023 | Southern Miss | 34 | at | UL Lafayette (6-7,3-5) | 31 | OT | ||
| 11/18/2023 | Southern Miss | 20 | at | Mississippi State (5-7) | 41 | at SEC | ||
| 11/25/2023 | Troy (11-3,8-1) | 35 | at | Southern Miss | 17 |
| vs Southern Miss | vs Other Opponents | Southern Miss compared to OOs | |
| Record: | 9-3 | 82-62 | |
| Points Scored: | 35.75 | 27.83 | -7.92 |
| Points Allowed: | 23.17 | 25.71 | -2.54 |
| Margin: | 12.58 | 2.12 | -10.46 |
| Total Points: | 58.92 | 53.54 | 5.38 |