| 9/2/2023 | Wofford (2-9) | 7 | at | Pittsburgh | 45 | SoCon (1AA) | ||
| 9/9/2023 | Cincinnati (3-9) | 27 | at | Pittsburgh | 21 | B12 | ||
| 9/16/2023 | Pittsburgh | 6 | at | West Virginia (9-4) | 17 | at B12 | ||
| 9/23/2023 | North Carolina (8-5,4-4) | 41 | at | Pittsburgh | 24 | |||
| 9/30/2023 | Pittsburgh | 21 | at | Virginia Tech (7-6,5-3) | 38 | |||
| 10/14/2023 | Louisville (10-4,7-2) | 21 | at | Pittsburgh | 38 | |||
| 10/21/2023 | Pittsburgh | 17 | at | Wake Forest (4-8,1-7) | 21 | |||
| 10/28/2023 | Pittsburgh | 7 | at | Notre Dame (10-3) | 58 | at ND | ||
| 11/4/2023 | Florida State (13-1,9-0) | 24 | at | Pittsburgh | 7 | |||
| 11/11/2023 | Pittsburgh | 13 | vs | Syracuse (6-7,2-6) | 28 | Bronx NY | ||
| 11/16/2023 | Boston College (7-6,3-5) | 16 | at | Pittsburgh | 24 | |||
| 11/25/2023 | Pittsburgh | 19 | at | Duke (8-5,4-4) | 30 |
| vs Pittsburgh | vs Other Opponents | Pittsburgh compared to OOs | |
| Record: | 9-3 | 78-64 | |
| Points Scored: | 27.33 | 28.17 | 0.84 |
| Points Allowed: | 20.17 | 24.28 | -4.11 |
| Margin: | 7.16 | 3.89 | -3.27 |
| Total Points: | 47.50 | 52.45 | -4.95 |