| 8/27/2022 | Union KY | 6 | at | Cumberlands KY (5-5,5-5) | 30 | |||
| 9/3/2022 | Lindsey Wilson (10-2,10-1) | 50 | at | Union KY | 3 | |||
| 9/10/2022 | Campbellsville (2-8,2-8) | 42 | at | Union KY | 14 | |||
| 9/17/2022 | Union KY | 10 | at | Bluefield (8-3,8-2) | 29 | |||
| 10/1/2022 | Kentucky Christian (3-8,3-7) | 42 | at | Union KY | 0 | |||
| 10/8/2022 | Union KY | 26 | at | St Andrews (1-10,1-9) | 27 | |||
| 10/22/2022 | Union KY | 13 | at | Point (4-7,4-6) | 16 | |||
| 10/29/2022 | Bluefield (8-3,8-2) | 54 | at | Union KY | 26 | |||
| 11/5/2022 | Union KY | 12 | at | Kentucky Christian (3-8,3-7) | 33 | |||
| 11/12/2022 | Reinhardt (8-2,8-2) | 40 | at | Union KY | 0 |
| vs Union KY | vs Other Opponents | Union KY compared to OOs | |
| Record: | 10-0 | 38-56 | |
| Points Scored: | 36.30 | 27.27 | -9.03 |
| Points Allowed: | 11.00 | 31.18 | -20.18 |
| Margin: | 25.30 | -3.91 | -29.21 |
| Total Points: | 47.30 | 58.45 | -11.15 |