| 9/3/2022 | Nebraska Wesleyan (1-9) | 31 | at | Eureka | 6 | ARC | ||
| 9/10/2022 | Eureka | 14 | at | Olivet (5-5) | 54 | at MIAA | ||
| 9/17/2022 | Rockford (1-9,0-8) | 14 | at | Eureka | 31 | |||
| 9/24/2022 | Ill. Benedictine (7-3,5-3) | 58 | at | Eureka | 10 | |||
| 10/1/2022 | Eureka | 27 | at | Concordia IL (3-7,2-6) | 13 | |||
| 10/8/2022 | Eureka | 20 | at | Concordia WI (8-3,6-2) | 23 | |||
| 10/15/2022 | Aurora (11-2,8-0) | 72 | at | Eureka | 13 | |||
| 10/22/2022 | Wisconsin Lutheran (4-6,4-4) | 51 | at | Eureka | 35 | |||
| 10/29/2022 | Eureka | 17 | at | Lakeland (3-7,3-5) | 26 | |||
| 11/5/2022 | Eureka | 7 | at | St Norbert (7-3,6-2) | 20 |
| vs Eureka | vs Other Opponents | Eureka compared to OOs | |
| Record: | 8-2 | 42-52 | |
| Points Scored: | 36.20 | 28.56 | -7.64 |
| Points Allowed: | 18.00 | 30.62 | -12.62 |
| Margin: | 18.20 | -2.06 | -20.26 |
| Total Points: | 54.20 | 59.18 | -4.98 |