| 9/4/2021 | Southwestern Texas (4-6) | 7 | at | Cal Lutheran | 37 | ASWC | ||
| 9/11/2021 | Pacific Lutheran (4-5) | 28 | at | Cal Lutheran | 42 | NWC | ||
| 9/18/2021 | Cal Lutheran | 25 | at | Puget Sound (1-9) | 21 | at NWC | ||
| 10/2/2021 | La Verne (3-6,3-5) | 14 | at | Cal Lutheran | 35 | |||
| 10/9/2021 | Cal Lutheran | vs | Pomona-Pitzer (4-5,3-4) | Canceled COVID | ||||
| 10/16/2021 | Cal Lutheran | 13 | at | Chapman (7-3,5-3) | 42 | |||
| 10/23/2021 | Claremont-Mudd-Scripps (7-3,6-2) | 27 | at | Cal Lutheran | 0 | |||
| 10/30/2021 | Whittier (0-9,0-8) | 8 | at | Cal Lutheran | 45 | |||
| 11/13/2021 | Cal Lutheran | 28 | at | Redlands (8-2,6-0) | 56 |
| vs Cal Lutheran | vs Other Opponents | Cal Lutheran compared to OOs | |
| Record: | 3-5 | 35-43 | |
| Points Scored: | 25.38 | 26.49 | 1.11 |
| Points Allowed: | 28.13 | 31.12 | -2.99 |
| Margin: | -2.75 | -4.63 | -1.88 |
| Total Points: | 53.51 | 57.61 | -4.10 |